Cellosaurus cell line AMU-ML1 (CVCL

Cellosaurus AMU-ML1 (CVCL_M583)

Cross-references
Cell line name	AMU-ML1
Accession	CVCL_M583
Resource Identification Initiative	To cite this cell line use: AMU-ML1 (RRID:CVCL_M583)
Comments	Population: Japanese. Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene fusion; HGNC; HGNC:990; BCL2 + HGNC; HGNC:5853; IGL; Name(s)=IGL-BCL2 (DOI=10.1182/blood.V118.21.5210.5210). Gene fusion; HGNC; HGNC:1001; BCL6 + HGNC; HGNC:5477; IGH; Name(s)=IGH-BCL6 (DOI=10.1182/blood.V118.21.5210.5210). Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (DOI=10.1182/blood.V118.21.5210.5210).
Disease	High grade B-cell lymphoma with MYC, BCL2, and BCL6 rearrangements (NCIt: C131913) High grade B-cell lymphoma with MYC and/or BCL2 and/or BCL6 rearrangement (ORDO: Orphanet_480541)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	60Y
Category	Cancer cell line
Publications	DOI=10.1182/blood.V118.21.5210.5210 Norikazu Tsunekawa, Ichiro Hanamura, Hidesuke Yamamoto, Hisao Nagoshi, Motohiro Wakabayashi, Natsumi Sakamoto, Tomohiro Horio, Mineaki Gotoh, Shohei Mizuno, Miyuki Takahashi, Kazuto Suganuma ...Show all 21 authors... , Mayuko Goto, Akihito Hiramatsu, Masaya Watarai, Masato Shikami, Akira Imamura, Hidetsugu Mihara, Tomohiko Taki, Masafumi Taniwaki, Hiroshi Miwa, Masakazu Nitta; Show fewer authors Establishment and characterization of a novel human cell line of triple hit lymphoma, AMU-ML1, carrying t(2;18)(p11.2;q21) and t(3;8;14)(q27;q24;q32) that involve BCL2, BCL6 and MYC. Blood 118 Suppl. 1:5210a-5210a(2011)
Encyclopedic resources	Wikidata; Q54749845
Entry history
Entry creation	05-Nov-2013
Last entry update	10-Apr-2025
Version number	15