Cellosaurus cell line HBL-2 [Human B-cell lymphoma] (CVCL

Cellosaurus HBL-2 [Human B-cell lymphoma] (CVCL_M573)

Cross-references
Cell line name	HBL-2 [Human B-cell lymphoma]
Accession	CVCL_M573
Resource Identification Initiative	To cite this cell line use: HBL-2 [Human B-cell lymphoma] (RRID:CVCL_M573)
Comments	Population: Chinese. Doubling time: ~20 hours (PubMed=3899542). Misspelling: AKA96-2; IARC_TP53=5997; Note=Not really a misspelling but an assignment of a name based on first author of publication and date because assignment of correct cell line name was not done correctly. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Arg (c.838A>C); ClinVar=VCV000926213; Zygosity=Unspecified (PubMed=8878455). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp281Gly (c.842A>G); ClinVar=VCV000141141; Zygosity=Unspecified (PubMed=8878455).
Disease	B-cell non-Hodgkin lymphoma (NCIt: C3457) B-cell non-Hodgkin lymphoma (ORDO: Orphanet_171915)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	17Y
Category	Cancer cell line
Publications	PubMed=3899542 Hong-Wen Peng, Lai-Lu Chong, Hung Chiang, Benjamin N. Chiang; Establishment and characterization of a new human lymphoma-derived cell line -- HBL-2. Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi 18:79-85(1985) PubMed=8558920 Wilhelm Gerhard Dirks, Margarete Zaborski, Kathrin Jager, Cecile Challier, Mami Shiota, Hilmar Quentmeier, Hans Gunther Drexler; The (2;5)(p23;q35) translocation in cell lines derived from malignant lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines. Leukemia 10:142-149(1996) PubMed=8878455; DOI=10.1111/j.1349-7006.1996.tb02122.x; PMCID=PMC5921203 Takashi Akasaka, Mikiko Muramatsu, Norimitsu Kadowaki, Hitoshi Ohno, Kanji Ishizaki, Hirohiko Yamabe, Shiro Fukuhara, Minoru Okuma; p53 mutation in B-cell lymphoid neoplasms with reference to oncogene rearrangements associated with chromosomal translocations. Jpn. J. Cancer Res. 87:930-937(1996)
Cell line databases/resources	cancercelllines; CVCL_M573
Encyclopedic resources	Wikidata; Q54881431
Polymorphism and mutation databases	IARC_TP53; 5997
Entry history
Entry creation	05-Nov-2013
Last entry update	19-Dec-2024
Version number	16