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Cellosaurus MM-S1 (CVCL_M538)

[Text version]
Cell line name MM-S1
Synonyms MM_S1; MM.S1
Accession CVCL_M538
Resource Identification Initiative To cite this cell line use: MM-S1 (RRID:CVCL_M538)
Comments Population: Japanese.
Characteristics: Produces Ig lambda.
Characteristics: IL6 dependent.
Doubling time: 24 hours (PubMed=2072743).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: Plasma cell; CL=CL_0000786.
Sequence variations
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A1SE (S6B45)
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=2167671; DOI=10.1016/0006-291x(90)90510-t
Yoshiaki Okuno, Takayuki Takahashi, Akira Suzuki, Shigemoto Ichiba, Kishiko Nakamura, Kiyotaka Hitomi, Ryuzo Sasaki, Hiroo Imura;
Expression of the erythropoietin receptor on a human myeloma cell line.
Biochem. Biophys. Res. Commun. 170:1128-1134(1990)

PubMed=1720489; DOI=10.1016/0145-2126(91)90110-f
Akira Suzuki, Takayuki Takahashi, Yoshiaki Okuno, Manabu Fukumoto, Hiroyasu Fukui, Yasuo Koishihara, Yoshiaki Ohsugi, Yohichiro Ohno, Hiroo Imura;
Estimation of interleukin 6 production by reverse transcriptase-polymerase chain reaction in four human myeloma cell lines.
Leuk. Res. 15:1043-1050(1991)

PubMed=2072743
Yoshiaki Okuno, Takayuki Takahashi, Akira Suzuki, Shigemoto Ichiba, Kishiko Nakamura, Manabu Fukumoto, Takamichi Okada, Hiromu Okada, Hiroo Imura;
Establishment and characterization of four myeloma cell lines which are responsive to interleukin-6 for their growth.
Leukemia 5:585-591(1991)

DOI=10.1007/0-306-46877-8_4
Helena Jernberg-Wiklund, Kenneth Nilsson;
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=11157491; DOI=10.1182/blood.V97.3.729
Marta Chesi, Leslie A. Brents, Sarah A. Ely, Carlos Bais, Davide F. Robbiani, Enrique A. Mesri, Walter Michael Kuehl, Peter Leif Bergsagel;
Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma.
Blood 97:729-736(2001)

PubMed=18647998; DOI=10.1093/jncimonographs/lgn011; PMCID=PMC2737184
Amel Dib, Ana Gabrea, Oleg K. Glebov, Peter Leif Bergsagel, Walter Michael Kuehl;
Characterization of MYC translocations in multiple myeloma cell lines.
J. Natl. Cancer Inst. Monogr. 39:25-31(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M538
Encyclopedic resources Wikidata; Q54906025
Polymorphism and mutation databases Cosmic; 720781
Cosmic; 2367271
Entry history
Entry creation05-Nov-2013
Last entry update14-Aug-2025
Version number19