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Cellosaurus Fravel (CVCL_M509)

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Cell line name Fravel
Synonyms FRAVEL; Fr
Accession CVCL_M509
Resource Identification Initiative To cite this cell line use: Fravel (RRID:CVCL_M509)
Comments Characteristics: Produces IgG kappa.
Doubling time: 62 hours (PubMed=6804081).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=6804081; DOI=10.1002/1097-0142(19820515)49:10<2091::AID-CNCR2820491021>3.0.CO;2-9
Claramae H. Miller, A.R. Carbonell, Rong Peng, Teresa G. Paglieroni, Malcolm Roff MacKenzie;
A human plasma cell line: induction and characterization.
Cancer 49:2091-2096(1982)

PubMed=2537114; DOI=10.1182/blood.V73.2.566.566
Christophe Duperray, Bernard Klein, Brian G.M. Durie, Xue-Guang Zhang, Michel Jourdan, Philippe Poncelet, Francois Favier, Claude Vincent, Jean Brochier, Gilbert Marcel Lenoir, Francois-Regis Bataille;
Phenotypic analysis of human myeloma cell lines.
Blood 73:566-572(1989)

PubMed=10087940; DOI=10.1016/S0165-4608(98)00157-5
Jeroen Kuipers, Jan Willem Vaandrager, Danielle Olde Weghuis, Peter Lees Pearson, Jacques Scheres, Henk Martinus Lokhorst, Hans Cornelius Clevers, Bert J.E.G. Bast;
Fluorescence in situ hybridization analysis shows the frequent occurrence of 14q32.3 rearrangements with involvement of immunoglobulin switch regions in myeloma cell lines.
Cancer Genet. Cytogenet. 109:99-107(1999)

DOI=10.1007/0-306-46877-8_4
Helena Jernberg-Wiklund, Kenneth Nilsson;
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54835156
Entry history
Entry creation05-Nov-2013
Last entry update14-Aug-2025
Version number12