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Cellosaurus ILKM8 (CVCL_M497)

[Text version]
Cell line name ILKM8
Synonyms ILKM-8
Accession CVCL_M497
Resource Identification Initiative To cite this cell line use: ILKM8 (RRID:CVCL_M497)
Comments Population: Japanese.
Characteristics: IL6 dependent.
Omics: Variations; Array-based CGH.
Cell type: B-cell; CL=CL_0000236.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E2UH (ILKM8 Lyn)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=10557056; DOI=10.1038/sj.leu.2401563
Yoshida S., Nakazawa N., Iida S., Hayami Y., Sato S., Wakita A., Shimizu S., Taniwaki M., Ueda R.
Detection of MUM1/IRF4-IgH fusion in multiple myeloma.
Leukemia 13:1812-1816(1999)

PubMed=11429052; DOI=10.1111/j.1349-7006.2001.tb01142.x; PMCID=PMC5926752
Hanamura I., Iida S., Akano Y., Hayami Y., Kato M., Miura K., Harada S., Banno S., Wakita A., Kiyoi H., Naoe T., Shimizu S., Sonta S.-i., Nitta M., Taniwaki M., Ueda R.
Ectopic expression of MAFB gene in human myeloma cells carrying (14;20)(q32;q11) chromosomal translocations.
Jpn. J. Cancer Res. 92:638-644(2001)

PubMed=15215163; DOI=10.1016/S0002-9440(10)63276-2; PMCID=PMC1618545
Inoue J., Otsuki T., Hirasawa A., Imoto I., Matsuo Y., Shimizu S., Taniwaki M., Inazawa J.
Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma.
Am. J. Pathol. 165:71-81(2004)

PubMed=17229644; DOI=10.3324/haematol.10300
Sanda T., Iida S., Kayukawa S., Ueda R.
Induction of class II major histocompatibility complex expression in human multiple myeloma cells by retinoid.
Haematologica 92:115-120(2007)

PubMed=20079716; DOI=10.1016/j.bbrc.2010.01.038
Iqbal M.S., Tsuyama N., Obata M., Ishikawa H.
A novel signaling pathway associated with Lyn, PI 3-kinase and Akt supports the proliferation of myeloma cells.
Biochem. Biophys. Res. Commun. 392:415-420(2010)

Cross-references
Cell line databases/resources CGH-DB; 9151-4
Encyclopedic resources Wikidata; Q54897486
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number12