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Cellosaurus CMA-03 (CVCL_M486)

[Text version]
Cell line name CMA-03
Synonyms CMA03
Accession CVCL_M486
Resource Identification Initiative To cite this cell line use: CMA-03 (RRID:CVCL_M486)
Comments Characteristics: Produces IgG kappa.
Characteristics: IL6 dependent.
Doubling time: 80 hours (PubMed=16266902).
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Peritoneal effusion; UBERON=UBERON_0001268.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_2G61 (CMA-03/06)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=16266902
Donata Verdelli, Michela Mattioli, Sonia Fabris, Lucia Nobili, Daniela Intini, Silvana Guerneri, Katia Todoerti, Alberto Zanella, Giorgio Lambertenghi-Deliliers, Luigia Lombardi, Antonino Neri;
Molecular and biological characterization of three novel interleukin-6-dependent human myeloma cell lines.
Haematologica 90:1541-1548(2005)

PubMed=17171682; DOI=10.1002/gcc.20404
Luigia Lombardi, Giulia Poretti, Michela Mattioli, Sonia Fabris, Luca Agnelli, Silvio Bicciato, Ivo Kwee, Andrea Rinaldi, Domenica Ronchetti, Donata Verdelli, Giorgio Lambertenghi-Deliliers ...Show all 13 authors... , Francesco Bertoni, Antonino Neri; Show fewer authors
Molecular characterization of human multiple myeloma cell lines by integrative genomics: insights into the biology of the disease.
Genes Chromosomes Cancer 46:226-238(2007)

PubMed=18700954; DOI=10.1186/1755-8794-1-37; PMCID=PMC2531129
Domenica Ronchetti, Marta Lionetti, Laura Mosca, Luca Agnelli, Adrian Andronache, Sonia Fabris, Giorgio Lambertenghi-Deliliers, Antonino Neri;
An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma.
BMC Med. Genomics 1:37.1-37.9(2008)

PubMed=19306352; DOI=10.1002/gcc.20660
Marta Lionetti, Luca Agnelli, Laura Mosca, Sonia Fabris, Adrian Andronache, Katia Todoerti, Domenica Ronchetti, Giorgio Lambertenghi-Deliliers, Antonino Neri;
Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles.
Genes Chromosomes Cancer 48:521-531(2009)

PubMed=24327544; DOI=10.1002/gcc.22127
Donata Verdelli, Lucia Nobili, Katia Todoerti, Laura Mosca, Sonia Fabris, Marianna D'Anca, Elisa Pellegrino, Roberto Piva, Giorgio Inghirami, Chiara Capelli, Martino Introna ...Show all 15 authors... , Luca Baldini, Raffaella Chiaramonte, Luigia Lombardi, Antonino Neri; Show fewer authors
Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line.
Genes Chromosomes Cancer 53:154-167(2014)

Cross-references
Encyclopedic resources Wikidata; Q54813731
Experimental variables resources EFO; EFO_0006552
Gene expression databases GEO; GSM143344
GEO; GSM290288
GEO; GSM977751
GEO; GSM977752
GEO; GSM977753
GEO; GSM977754
GEO; GSM977755
GEO; GSM977756
Polymorphism and mutation databases Cosmic; 2391808
Entry history
Entry creation05-Nov-2013
Last entry update14-Aug-2025
Version number15