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Cellosaurus MCF3B (CVCL_M373)

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Cell line name MCF3B
Accession CVCL_M373
Resource Identification Initiative To cite this cell line use: MCF3B (RRID:CVCL_M373)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=RGD; 69267; Slc5a5.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=11079502
Yuji Nakamoto, Tsuneo Saga, Takashi Misaki, Hisataka Kobayashi, Noriko Sato, Takayoshi Ishimori, Shinji Kosugi, Harumi Sakahara, Junji Konishi;
Establishment and characterization of a breast cancer cell line expressing Na+/I-symporters for radioiodide concentrator gene therapy.
J. Nucl. Med. 41:1898-1904(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M373
Encyclopedic resources Wikidata; Q54904448
Entry history
Entry creation05-Nov-2013
Last entry update19-Dec-2024
Version number19