Cellosaurus logo
expasy logo

Cellosaurus XP25BE LCL (CVCL_M289)

[Text version]
Cell line name XP25BE LCL
Synonyms Xeroderma Pigmentosum 25 BEthesda LCL; GM04490; KR04490
Accession CVCL_M289
Resource Identification Initiative To cite this cell line use: XP25BE LCL (RRID:CVCL_M289)
Comments Population: African American.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:12816; XPC; Unexplicit; IVS11-1_IVS11-2delAG; Zygosity=Homozygous (PubMed=16081512).
  • Mutation; HGNC; HGNC:12816; XPC; Unexplicit; IVS11-6_IVS11-7insCC; Zygosity=Homozygous (PubMed=16081512).
Disease Xeroderma pigmentosum, complementation group C (NCIt: C114770)
Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_M288 ! XP25BE
Sex of cell Female
Age at sampling 7Y
Category Transformed cell line
Publications

PubMed=16081512; DOI=10.1093/carcin/bgi204
Sikandar G. Khan, Kyu-Seon Oh, Tala Shahlavi, Takahiro Ueda, David B. Busch, Hiroki Inui, Steffen Emmert, Kyoko Imoto, Vanessa Muniz-Medina, Carl C. Baker, John Joseph DiGiovanna ...Show all 18 authors... , Deborah Schmidt, Arash Khadavi, Ahmet Metin, Engin Mevlut Gozukara, Hanoch Slor, Alain Sarasin, Kenneth H. Kraemer; Show fewer authors
Reduced XPC DNA repair gene mRNA levels in clinically normal parents of xeroderma pigmentosum patients.
Carcinogenesis 27:84-94(2006)

Cross-references
Cell line collections (Providers) Coriell; GM04490
Cell line databases/resources CLO; CLO_0019668
Biological sample resources BioSample; SAMN00795297
Encyclopedic resources Wikidata; Q54838537
Entry history
Entry creation05-Nov-2013
Last entry update19-Dec-2024
Version number16