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Cellosaurus MH3-XPD (CVCL_M229)

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Cell line name MH3-XPD
Accession CVCL_M229
Resource Identification Initiative To cite this cell line use: MH3-XPD (RRID:CVCL_M229)
Comments Doubling time: 32 hours (PubMed=3030788).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV7).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:3434; ERCC2; Simple; p.Arg683Trp (c.2047C>T); ClinVar=VCV000016793; Zygosity=Homozygous (from parent cell line).
Disease Xeroderma pigmentosum, complementation group D (NCIt: C3967)
Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_L754 (XP3NE)
Sex of cell Male
Age at sampling 28Y
Category Transformed cell line
Publications

PubMed=3030788; DOI=10.1016/0014-4827(87)90214-X
Cada M. Wood, Terry L. Timme, Myra McEarl Hurt, Bill R. Brinkley, David Hamilton Ledbetter, Robb E. Moses;
Transformation of DNA repair-deficient human diploid fibroblasts with a simian virus 40 plasmid.
Exp. Cell Res. 169:543-553(1987)

Cross-references
Encyclopedic resources Wikidata; Q54905529
Entry history
Entry creation06-May-2013
Last entry update19-Dec-2024
Version number16