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Cellosaurus REN (CVCL_M202)

[Text version]
Cell line name REN
Synonyms Ren
Accession CVCL_M202
Resource Identification Initiative To cite this cell line use: REN (RRID:CVCL_M202)
Comments Characteristics: Established from a SCID nude mouse xenograft (PubMed=8010779).
Miscellaneous: STR profile from personal communication of Pentimalli, Francesca.
Miscellaneous: Sex and age of donor and site of origin from personal communication of Smythe, William Roy through Pentimalli, Francesca.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C8CW (REN/green)CVCL_C8CX (REN/luc)
Sex of cell Male
Age at sampling 73Y
Category Cancer cell line
Publications

PubMed=8010779; DOI=10.1016/0003-4975(94)90090-6
William Roy Smythe, Larry R. Kaiser, Harry C. Hwang, Kunjiata M. Amin, Joseph Mark Pilewski, Stephen L. Eck, James M. Wilson, Steven M. Albelda;
Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma.
Ann. Thorac. Surg. 57:1395-1401(1994)

PubMed=8174104
William Roy Smythe, Harry C. Hwang, Kunjiata M. Amin, Stephen L. Eck, Beverly L. Davidson, James M. Wilson, Larry R. Kaiser, Steven M. Albelda;
Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system.
Cancer Res. 54:2055-2059(1994)

PubMed=12063468; DOI=10.1067/mtc.2002.121684
William Roy Smythe, Imran Mohuiddin, Mustafa Ozveran, Xiao-Bo Cao;
Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product.
J. Thorac. Cardiovasc. Surg. 123:1191-1198(2002)

PubMed=12707267; DOI=10.1074/jbc.M302161200
Claire Vivo, Wei-Hong Liu, Virginia Courtney Broaddus;
c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells.
J. Biol. Chem. 278:25461-25467(2003)

PubMed=18223230; DOI=10.1158/1078-0432.CCR-07-1388
Pietro Bertino, Federica Piccardi, Camillo Porta, Roberto E. Favoni, Michele Cilli, Luciano Mutti, Giovanni Gaudino;
Imatinib mesylate enhances therapeutic effects of gemcitabine in human malignant mesothelioma xenografts.
Clin. Cancer Res. 14:541-548(2008)

PubMed=22552293; DOI=10.1158/0008-5472.CAN-11-3481; PMCID=PMC3389268
Sandro Jube, Zeyana S. Rivera, Marco Emilio Bianchi, Amy Powers, Ena Wang, Ian Pagano, Harvey I. Pass, Giovanni Gaudino, Michele Carbone, Hai-Ning Yang;
Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma.
Cancer Res. 72:3290-3301(2012)

Cross-references
Encyclopedic resources Wikidata; Q54949728
Experimental variables resources EFO; EFO_0022351
Polymorphism and mutation databases Cosmic; 1963334
Entry history
Entry creation06-May-2013
Last entry update10-Sep-2024
Version number12