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Cellosaurus COG-LL-384h (CVCL_M166)

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Cell line name COG-LL-384h
Synonyms COG-LL-384
Accession CVCL_M166
Resource Identification Initiative To cite this cell line use: COG-LL-384h (RRID:CVCL_M166)
Comments Characteristics: Hypoxic cell line grown at 5% O2.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: T-cell; CL=CL_0000084.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D5J5 ! COG-LY-357h
Sex of cell Male
Age at sampling Children
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX,Y
CSF1PO12
D2S133819,20
D3S135815
D5S81811
D7S82010,12
D8S117910,13
D13S3179,12
D16S5399,12
D18S5112,21
D19S43313,15.2
D21S1129
FGA23,24
TH016
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Web pages Provider; CCR; -; https://www.cccells.org/PDF_Files/LL-PDX/COG-LL-384h.pdf
Provider; CCR; -; https://www.cccells.org/tables/Lymphoid.php
Publications

PubMed=19298590; DOI=10.1111/j.1365-2141.2009.07631.x
Min H. Kang, Narine Harutyunyan, Connor P. Hall, Rachael A. Papa, Richard B. Lock;
Methotrexate and aminopterin exhibit similar in vitro and in vivo preclinical activity against acute lymphoblastic leukaemia and lymphoma.
Br. J. Haematol. 145:389-393(2009)

PubMed=22137317; DOI=10.1016/j.leukres.2011.10.022; PMCID=PMC3264762
Chong Zhang, Yong-Ku Ryu, Taylor Z. Chen, Connor P. Hall, Daniel R. Webster, Min H. Kang;
Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis.
Leuk. Res. 36:342-349(2012)

Cross-references
Encyclopedic resources Wikidata; Q54813976
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number14