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Cellosaurus COG-LL-355h (CVCL_M164)

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Cell line name COG-LL-355h
Accession CVCL_M164
Resource Identification Initiative To cite this cell line use: COG-LL-355h (RRID:CVCL_M164)
Comments Characteristics: Hypoxic cell line grown at 5% O2.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B3TK ! COG-LL-355
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133819
D3S135814,15
D5S81812
D7S82010,11
D8S117912,16
D13S31712,13
D16S5399,11
D18S5112
D19S43314
D21S1128,30
FGA19,23
TH019,9.3
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Web pages Provider; CCR; -; https://www.cccells.org/cellreqs-leuk.php
Provider; CCR; -; https://www.cccells.org/PDF_Files/LL-PDX/COG-LL-355.pdf
Publications

PubMed=22137317; DOI=10.1016/j.leukres.2011.10.022; PMCID=PMC3264762
Chong Zhang, Yong-Ku Ryu, Taylor Z. Chen, Connor P. Hall, Daniel R. Webster, Min H. Kang;
Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis.
Leuk. Res. 36:342-349(2012)

PubMed=26080839; DOI=10.1158/1078-0432.CCR-15-0114; PMCID=PMC4681691
Connor P. Hall, Charles Patrick Reynolds, Min H. Kang;
Modulation of glucocorticoid resistance in pediatric T-cell acute lymphoblastic leukemia by increasing BIM expression with the PI3K/mTOR inhibitor BEZ235.
Clin. Cancer Res. 22:621-632(2016)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5; PMCID=PMC8967900
Isabelle Rose Leo, Luay Aswad, Matthias Stahl, Elena Kunold, Frederik Post, Tom Erkers, Nona Struyf, Georgios Mermelekas, Rubin Narayan Joshi, Eva Gracia-Villacampa, Paivi Ostling ...Show all 17 authors... , Olli-Pekka Kallioniemi, Katja Pokrovskaja Tamm, Ioannis Siavelis, Janne Lehtio, Mattias Vesterlund, Rozbeh Jafari; Show fewer authors
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cross-references
Encyclopedic resources Wikidata; Q54813974
Gene expression databases GEO; GSM5137713
GEO; GSM5137754
Proteomic databases PRIDE; PXD023662
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number13