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Cellosaurus CHLA-266 (CVCL_M149)

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Cell line name CHLA-266
Synonyms CHLA266
Accession CVCL_M149
Resource Identification Initiative To cite this cell line use: CHLA-266 (RRID:CVCL_M149)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: NCI Pediatric Preclinical Testing Program (PPTP) cell line panel.
Doubling time: 40 hours (CelloPub=CLPUB00418); 45 hours (PubMed=22120608); 50 hours (PubMed=20922763).
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Brain, posterior fossa; UBERON=UBERON_0008788.
Disease Atypical teratoid/rhabdoid tumor (NCIt: C6906)
Atypical teratoid rhabdoid tumor (ORDO: Orphanet_99966)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 2Y6M
Category Cancer cell line
STR profile Source(s): COG; PubMed=20922763; PubMed=22120608

Markers:
AmelogeninX
CSF1PO10,11
D2S133820
D3S135815,18
D5S81810,12
D7S82010,12
D8S117910,14
D13S3179,10
D16S53910,12
D18S5117,19
D19S43313,14
D21S1129
FGA23,24
TH016,7
TPOX8,11
vWA15,17

Run an STR similarity search on this cell line
Web pages Provider; CCR; -; https://www.cccells.org/tables/Brain_N.php
Publications

CLPUB00418
Jing-Ying Xu, Anat Erdreich-Epstein, Jaclyn A. Biegel, Charles Patrick Reynolds;
Fenretinide combined with thiotepa is active against 3 newly established atypical teratoid rhabdoid tumor cell lines that manifest high-level multidrug resistance.
Cancer Res. 68 Suppl. 9:3743-3743(2008)

PubMed=20922763; DOI=10.1002/pbc.22801; PMCID=PMC3005554
Min H. Kang, Malcolm A. Smith, Christopher L. Morton, Nino Keshelava, Peter J. Houghton, Charles Patrick Reynolds;
National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.
Pediatr. Blood Cancer 56:239-249(2011)

PubMed=22120608; DOI=10.1007/s11060-011-0756-5; PMCID=PMC3379550
Jing-Ying Xu, Anat Erdreich-Epstein, Ignacio Gonzalez-Gomez, Elizabeth Y. Melendez, Goar Smbatyan, Rex A. Moats, Michael Rosol, Jaclyn A. Biegel, Charles Patrick Reynolds;
Novel cell lines established from pediatric brain tumors.
J. Neurooncol. 107:269-280(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M149
Cell_Model_Passport; SIDM01537
DepMap; ACH-001031
Encyclopedic resources Wikidata; Q54812496
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number17