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Cellosaurus LNCaP C-51 (CVCL_M130)

[Text version]
Cell line name LNCaP C-51
Synonyms LNCaP-C51 C-51; C51
Accession CVCL_M130
Resource Identification Initiative To cite this cell line use: LNCaP C-51 (RRID:CVCL_M130)
Comments Population: Caucasian.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_M129 (LNCaP C-33)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=11705865
Karan D., Schmied B.M., Dave B.J., Wittel U.A., Lin M.-F., Batra S.K.
Decreased androgen-responsive growth of human prostate cancer is associated with increased genetic alterations.
Clin. Cancer Res. 7:3472-3480(2001)

PubMed=11870800; DOI=10.1002/pros.10054
Igawa T., Lin F.-F., Lee M.-S., Karan D., Batra S.K., Lin M.-F.
Establishment and characterization of androgen-independent human prostate cancer LNCaP cell model.
Prostate 50:222-235(2002)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M130
Encyclopedic resources Wikidata; Q54902823
Entry history
Entry creation06-May-2013
Last entry update05-Oct-2023
Version number16