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Cellosaurus PC-5 [Human prostate carcinoma] (CVCL_M124)

[Text version]
Cell line name PC-5 [Human prostate carcinoma]
Accession CVCL_M124
Resource Identification Initiative To cite this cell line use: PC-5 [Human prostate carcinoma] (RRID:CVCL_M124)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=8200854; DOI=10.1111/j.1349-7006.1994.tb02376.x; PMCID=PMC5919474
Ryu-ichi Fujii, Masato Mutoh, Kiyoshi Niwa, Kazutaka Yamada, Takashi Aikou, Masayuki Nakagawa, Michihiko Kuwano, Shin-ichi Akiyama;
Active efflux system for cisplatin in cisplatin-resistant human KB cells.
Jpn. J. Cancer Res. 85:426-433(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M124
Encyclopedic resources Wikidata; Q54938458
Entry history
Entry creation06-May-2013
Last entry update19-Dec-2024
Version number16