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Cellosaurus GRX (CVCL_M115)

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Cell line name GRX
Accession CVCL_M115
Resource Identification Initiative To cite this cell line use: GRX (RRID:CVCL_M115)
Comments Characteristics: Established from fibrotic granulomas induced in C3H/HeN mice liver by experimental infection with Schistosoma mansoni (PubMed=2126187).
Derived from site: In situ; Liver; Note=From a granulomatous inflammation; UBERON=UBERON_0002107.
Cell type: Hepatic stellate cell; CL=CL_0000632.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/HeN.
Hierarchy Parent: CVCL_HA25 (GR [Mouse liver])
Sex of cell Sex unspecified
Age at sampling 4M
Category Spontaneously immortalized cell line
STR profile Source(s): PubMed=35563813

Markers:
Mouse STR 1-110
Mouse STR 1-216
Mouse STR 2-19
Mouse STR 3-214
Mouse STR 4-219.3
Mouse STR 5-515
Mouse STR 6-419
Mouse STR 6-712
Mouse STR 7-126
Mouse STR 8-116
Mouse STR 11-216
Mouse STR 12-116
Mouse STR 13-117
Mouse STR 15-325.3
Mouse STR 17-216
Mouse STR 18-316
Mouse STR 19-212
Mouse STR X-126,27

Run an STR similarity search on this cell line
Publications

PubMed=4030623; DOI=10.1007/BF02623469
Radovan Borojevic, Alvaro N.A. Monteiro, Solange A. Vinhas, Gilberto Barbosa Domont, Paulo Antonio Souza Mourao, Herve Emonard, Gabriel Grimaldi Jr., Jean-Alexis Grimaud;
Establishment of a continuous cell line from fibrotic schistosomal granulomas in mice livers.
In Vitro Cell. Dev. Biol. 21:382-390(1985)

PubMed=2126187; PMCID=PMC2002367
Luiz-Claudio F. Silva, Radovan Borojevic, Paulo Antonio Souza Mourao;
Identification of cells responsible for synthesis of sulphated glycosaminoglycans in schistosome-induced hepatic granulomas.
Int. J. Exp. Pathol. 71:845-856(1990)

PubMed=17760834; DOI=10.1111/j.1582-4934.2007.00060.x; PMCID=PMC3823251
Jens Herrmann, Axel M. Gressner, Ralf Weiskirchen;
Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function?
J. Cell. Mol. Med. 11:704-722(2007)

PubMed=35563813; DOI=10.3390/cells11091504; PMCID=PMC9102025
Sarah K. Schroder, Herdit M. Schuler, Kamilla V. Petersen, Cinzia Tesauro, Birgitta Rudd Knudsen, Finn Skou Pedersen, Frederike Krus, Eva Miriam Buhl, Elke Roeb, Martin Roderfeld, Radovan Borojevic ...Show all 13 authors... , Jamie L. Almeida, Ralf Weiskirchen; Show fewer authors
Genetic and molecular characterization of the immortalized murine hepatic stellate cell line GRX.
Cells 11:1504.1-1504.20(2022)

Cross-references
Cell line collections (Providers) BCRJ; 0094
Anatomy/cell type resources BTO; BTO_0003528
Encyclopedic resources Wikidata; Q54871708
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number15