• Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1237Glufs*2 (c.3709_3710delCA); ClinVar=VCV000433651; Zygosity=Unspecified (PubMed=24755471).
  
• Mutation; HGNC; HGNC:583; APC; Simple; p.His1490fs*17 (c.4469delA); Zygosity=Unspecified (PubMed=24755471).
  
• Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Unspecified (PubMed=24755471).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr125Met (c.374C>T); ClinVar=VCV000183748; Zygosity=Unspecified (PubMed=16418264).
  

PubMed=10051639; DOI=10.1073/pnas.96.5.2316; PMCID=PMC26781
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