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Cellosaurus JMN-1B (CVCL_M006)

[Text version]
Cell line name JMN-1B
Synonyms JMN 1B; JMN1B
Accession CVCL_M006
Resource Identification Initiative To cite this cell line use: JMN-1B (RRID:CVCL_M006)
Comments Population: Caucasian.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Homozygous (from parent cell line).
Disease Pleural biphasic mesothelioma (NCIt: C45665)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_M005 (JMN)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
Publications

PubMed=2787682; DOI=10.1182/blood.V74.3.940.940
George Daniel Demetri, Beatrice Wistar Zenzie, James George Rheinwald, James Douglas Griffin;
Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro.
Blood 74:940-946(1989)

PubMed=15920167; DOI=10.1016/S0002-9440(10)62492-3; PMCID=PMC1363736
Gavin J. Gordon, Graham N. Rockwell, Roderick V. Jensen, James George Rheinwald, Jonathan Neil Glickman, Joshua Paul Aronson, Brian J. Pottorf, Matthew David Nitz, William G. Richards, David John Sugarbaker, Raphael Bueno;
Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling.
Am. J. Pathol. 166:1827-1840(2005)

PubMed=19853261; DOI=10.1016/j.jtcvs.2009.06.027
Mor-Li Hartman, John Matthew Esposito, Beow Yong Yeap, David John Sugarbaker;
Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma.
J. Thorac. Cardiovasc. Surg. 139:1233-1240(2010)

Cross-references
Encyclopedic resources Wikidata; Q54899009
Gene expression databases GEO; GSM49617
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number12