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Cellosaurus OCI-m/F1 (CVCL_LN39)

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Cell line name OCI-m/F1
Accession CVCL_LN39
Resource Identification Initiative To cite this cell line use: OCI-m/F1 (RRID:CVCL_LN39)
Comments Problematic cell line: Contaminated. Grand-parent cell line (Ej138) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_LN38 (MGH-U1/OCI)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=3409229
Asya Kovnat, Ronald N. Buick, Barbara Choo, Etienne de Harven, Irina Kopelyan, Jeffrey M. Trent, Ian F. Tannock;
Malignant properties of sublines selected from a human bladder cancer cell line that contains an activated c-Ha-ras oncogene.
Cancer Res. 48:4993-5000(1988)

Cross-references
Cell line databases/resources cancercelllines; CVCL_LN39
Encyclopedic resources Wikidata; Q54931780
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number12