Cellosaurus cell line CCC-5 (CVCL

Cellosaurus CCC-5 (CVCL_LM83)

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Cell line name

CCC-5

Synonyms

CCC5

Accession

CVCL_LM83

Resource Identification Initiative

To cite this cell line use: CCC-5 (RRID:CVCL_LM83)

Comments

Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 60.5 hours (CelloPub=CLPUB00408); 2-3 days (DSMZ=ACC-810).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (DepMap=ACH-002647).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Unspecified (CelloPub=CLPUB00408).

Disease

Cholangiocarcinoma (NCIt: C4436)
Cholangiocarcinoma (ORDO: Orphanet_70567)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

59Y

Category

Cancer cell line

STR profile

Source(s): DSMZ=ACC-810

Markers:

Amelogenin	X
CSF1PO	10,11
D2S1338	20,25
D3S1358	14,17
D5S818	11,13
D7S820	10,11
D8S1179	14,15
D13S317	12
D16S539	11,12
D18S51	15
D19S433	14
D21S11	29,31
FGA	24
Penta D	9,10
Penta E	13,14
TH01	6,9.3
TPOX	8
vWA	16

Publications

CLPUB00408
Sebastian Zach, Johanna Grun, Alexander T. Bauer, Christian Pilarsky, Robert Grutzmann, Hong-Lei Weng, Steven Dooley, Torsten J. Wilhelm, Timo Gaiser, Felix Ruckert;
CCC-5, a new primary cholangiocellular cell line.
Int. J. Clin. Exp. Pathol. 10:2451-2460(2017)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Abdulkadir Isidan, Ali Yenigun, Daiki Soma, Eric Aksu, Kevin Lopez, Yujin Park, Arthur Cross-Najafi, Ping Li, Debjyoti Kundu, Michael G. House, Sanjukta Chakraborty ...Show all 17 authors... , Shannon Glaser, Lindsey Kennedy, Heather Francis, Wen-Jun Zhang, Gianfranco D. Alpini, Burcin Ekser; Show fewer authors
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vindhya Vijay, Negin Karisani, Lei Shi, Yu-Han Hung, Phuong Vu, Prabhat Kattel, Lauren Kenney, Joshua Merritt, Ramzi Adil, Qi-Biao Wu, Yuan-Li Zhen ...Show all 39 authors... , Robert Morris, Johannes Kreuzer, Meena Kathiresan, Xcanda Ixchel Herrera Lopez, Haley Ellis, Ilaria G. Gritti, Lilian Lecorgne, Ines Farag, Alexandra Popa, William Shen, Hiroyuki Kato, Qin Xu, Eranga Roshan Balasooriya, Meng-Ju Wu, Saireudee Chaturantabut, Robin Kate Kelley, James Mark Cleary, Michael Scott Lawrence, David E. Root, Cyril Henri Benes, Vikram Deshpande, Dejan Juric, William Raj Sellers, Cristina Rosa Ferrone, Wilhelm Haas, Francisca Vazquez, Gad Getz, Nabeel M. Bardeesy; Show fewer authors
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references

Cell line collections (Providers)

DSMZ; ACC-810

Cell line databases/resources

cancercelllines; CVCL_LM83
DepMap; ACH-002647
DSMZCellDive; ACC-810

Encyclopedic resources

Wikidata; Q54808767

Entry history

Entry creation

15-Nov-2017

Last entry update

19-Dec-2024

Version number