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Cellosaurus ciPTEC-OAT1 (CVCL_LI01)

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Cell line name ciPTEC-OAT1
Accession CVCL_LI01
Resource Identification Initiative To cite this cell line use: ciPTEC-OAT1 (RRID:CVCL_LI01)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:10970; SLC22A6.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Kidney, proximal tubule; UBERON=UBERON_0004134.
Cell type: Epithelial cell of proximal tubule; CL=CL_0002306.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_W184 (ciPTEC)
Sex of cell Female
Age at sampling 12Y
Category Conditionally immortalized cell line
Publications

PubMed=26821801; DOI=10.1208/s12248-016-9871-8; PMCID=PMC4779111
Tom T.G. Nieskens, Janny G.P. Peters, Marieke J. Schreurs, Niels Smits, Rob Woestenenk, Katja Jansen, Thom K. van der Made, Melanie Roring, Constanze Hilgendorf, Martijn J. Wilmer, Rosalinde Masereeuw;
A human renal proximal tubule cell line with stable organic anion transporter 1 and 3 expression predictive for antiviral-induced toxicity.
AAPS J. 18:465-475(2016)

Cross-references
Encyclopedic resources Wikidata; Q54813369
Entry history
Entry creation15-Nov-2017
Last entry update14-Aug-2025
Version number12