Cellosaurus cell line CHO-K1 tsTM13 (CVCL

Cellosaurus CHO-K1 tsTM13 (CVCL_LH73)

Cross-references
Cell line name	CHO-K1 tsTM13
Synonyms	tsTM13
Accession	CVCL_LH73
Resource Identification Initiative	To cite this cell line use: CHO-K1 tsTM13 (RRID:CVCL_LH73)
Comments	Characteristics: Temperature sensitive. Exhibits a delayed cell cycle progression from metaphase to telophase at a non-permissive temperature of 39 Celsius and is finally arrested from anaphase to telophase. Transformant: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). Derived from site: In situ; Ovary; UBERON=UBERON_0000992. Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy	Parent: CVCL_0214 (CHO-K1)
Sex of cell	Female
Age at sampling	Adult
Category	Transformed cell line
Publications	PubMed=2237640; DOI=10.1007/BF01233196 Hideo Tsuji, Yasushi Matsudo, Satsuki Tsuji, Fumio Hanaoka, Masao Hyodo, Tada-aki Hori; Isolation of temperature-sensitive CHO-K1 cell mutants exhibiting chromosomal instability and reduced DNA synthesis at nonpermissive temperature. Somat. Cell Mol. Genet. 16:461-476(1990) PubMed=1309502; DOI=10.1016/0014-4827(92)90372-F Hideo Tsuji, Yasushi Matsudo, Kozo Ajiro, Hideyo Yasuda, Fumio Hanaoka, Akiko Hayashi, Shunsaku Utsumi, Yoshiki Ohba, Tada-aki Hori; A temperature-sensitive CHO-K1 cell mutant (tsTM13) defective in chromosome decondensation and spindle deconstruction in M phase. Exp. Cell Res. 198:201-213(1992) PubMed=8944784; DOI=10.1111/j.1432-1033.1996.00923.x Kozo Ajiro, Hideyo Yasuda, Hideo Tsuji; Vanadate triggers the transition from chromosome condensation to decondensation in a mitotic mutant (tsTM13) inactivation of p34cdc2/H1 kinase and dephosphorylation of mitosis-specific histone H3. Eur. J. Biochem. 241:923-930(1996)
Encyclopedic resources	Wikidata; Q54973161
Entry history
Entry creation	15-Nov-2017
Last entry update	19-Dec-2024
Version number	9