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Cellosaurus C57MG/2-69-23 (CVCL_LF86)

[Text version]
Cell line name C57MG/2-69-23
Synonyms 2-69-23
Accession CVCL_LF86
Resource Identification Initiative To cite this cell line use: C57MG/2-69-23 (RRID:CVCL_LF86)
Comments Group: Patented cell line.
Characteristics: The expression of the Wnt1 gene is under the control of a tetracycline-repressible promoter.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98953; Wnt1.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_6824 (C57MG)
Sex of cell Female
Age at sampling 23W
Category Spontaneously immortalized cell line
Publications

PubMed=9488439; DOI=10.1128/mcb.18.3.1248; PMCID=PMC108837
Vladimir Korinek, Nick Barker, Karl Willert, Miranda Molenaar, Jeroen P. Roose, Gerry Wagenaar, Marry Markman, Wout Lamers, Olivier Destree, Hans Cornelius Clevers;
Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.
Mol. Cell. Biol. 18:1248-1256(1998)

Patent=WO1999043804A1
Nick Barker, Vladimir Korinek, Hans Cornelius Clevers;
Mouse Tcf-3 and Tcf-4 and tumourigenesis related to wnt/wingless signalling.
Patent number WO1999043804A1, 02-Sep-1999

PubMed=11358845
Wayne Szeto, Wen Jiang, David A. Tice, Bonnee Rubinfeld, Philip G. Hollingshead, Sharon E. Fong, Debra L. Dugger, Thinh Pham, Daniel G. Yansura, Terence A. Wong, J. Christopher Grimaldi ...Show all 21 authors... , Racquel T. Corpuz, Jennifer S. Singh, Gretchen D. Frantz, Brigitte Devaux, Craig W. Crowley, Ralph H. Schwall, David A. Eberhard, Luca Rastelli, Paul Polakis, Diane Pennica; Show fewer authors
Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid.
Cancer Res. 61:4197-4205(2001)

PubMed=11832495; DOI=10.1074/jbc.M200334200
David A. Tice, Wayne Szeto, Irina Soloviev, Bonnee Rubinfeld, Sharon E. Fong, Debra L. Dugger, Jane Winer, P. Mickey Williams, David Wieand, Victoria Smith, Ralph H. Schwall ...Show all 13 authors... , Diane Pennica, Paul Polakis; Show fewer authors
Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling.
J. Biol. Chem. 277:14329-14335(2002)

Cross-references
Encyclopedic resources Wikidata; Q54808204
Entry history
Entry creation15-Nov-2017
Last entry update10-Sep-2024
Version number8