Cellosaurus logo
expasy logo

Cellosaurus TSEC (CVCL_LF84)

[Text][XML][JSON]
Cell line name TSEC
Synonyms Transformed Sinusoidal Endothelial Cells
Accession CVCL_LF84
Resource Identification Initiative To cite this cell line use: TSEC (RRID:CVCL_LF84)
Comments Doubling time: ~10 hours (PubMed=20644520).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Endothelial cell of hepatic sinusoid; CL=CL_1000398.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=20644520; DOI=10.1038/labinvest.2010.132; PMCID=PMC2992582
Robert C. Huebert, Kumaravelu Jagavelu, Ann F. Liebl, Bing Q. Huang, Patrick L. Splinter, Nicholas F. LaRusso, Raul A. Urrutia, Vijay H. Shah;
Immortalized liver endothelial cells: a cell culture model for studies of motility and angiogenesis.
Lab. Invest. 90:1770-1781(2010)

PubMed=27454769; DOI=10.1371/journal.pone.0159217; PMCID=PMC4959750
Rachel H. McMahan, Cara E. Porsche, Michael G. Edwards, Hugo Ramen Rosen;
Free fatty acids differentially downregulate chemokines in liver sinusoidal endothelial cells: insights into non-alcoholic fatty liver disease.
PLoS ONE 11:e0159217.1-e0159217.14(2016)

Cross-references
Encyclopedic resources Wikidata; Q54973118
Gene expression databases GEO; GSE67651
Entry history
Entry creation15-Nov-2017
Last entry update27-Nov-2025
Version number7