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Cellosaurus HPSI0516i-yist_3 (CVCL_LF16)

[Text version]
Cell line name HPSI0516i-yist_3
Synonyms WTSIi623-A
Accession CVCL_LF16
Resource Identification Initiative To cite this cell line use: HPSI0516i-yist_3 (RRID:CVCL_LF16)
Comments From: University College London; London; United Kingdom.
From: Wellcome Trust Sanger Institute; Hinxton; United Kingdom.
Population: Caucasian and Chinese.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:2206; COL4A4; Simple; p.Pro1096Ser (c.3286C>T); Zygosity=Heterozygous (PubMed=35076391).
  • Mutation; HGNC; HGNC:2207; COL4A5; Simple; p.Gly1232Asp (c.3695G>A); Zygosity=Hemizygous (PubMed=35076391).
Disease Alport syndrome (NCIt: C34842)
Alport syndrome (ORDO: Orphanet_63)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_LF15 ! HPSI0516i-yist_1
Sex of cell Male
Age at sampling 22Y
Category Induced pluripotent stem cell
Publications

PubMed=35076391; DOI=10.7554/eLife.73486; PMCID=PMC8849328
Mychel Raony Paiva Teixeira Morais, Pin-Yuan Tian, Craig Lawless, Syed Murtuza-Baker, Louise Hopkinson, Steven Woods, Aleksandr Mironov, David Andrew Long, Daniel P. Gale, Telma Maria Tenorio Zorn, Susan J. Kimber ...Show all 13 authors... , Roy Zent, Rachel Lennon; Show fewer authors
Kidney organoids recapitulate human basement membrane assembly in health and disease.
eLife 11:e73486.1-e73486.30(2022)

Cross-references
Cell line collections (Providers) ECACC; 77650724
Cell line databases/resources HipSci; HPSI0516i-yist_3
hPSCreg; WTSIi623-A
Biological sample resources BioSamples; SAMEA4673668
Encyclopedic resources Wikidata; Q54890987
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number11