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Cellosaurus HPSI0516i-yist_3 (CVCL_LF16)

[Text version]
Cell line name HPSI0516i-yist_3
Synonyms WTSIi623-A
Accession CVCL_LF16
Resource Identification Initiative To cite this cell line use: HPSI0516i-yist_3 (RRID:CVCL_LF16)
Comments From: University College London; London; United Kingdom.
From: Wellcome Trust Sanger Institute; Hinxton; United Kingdom.
Population: Caucasian and Chinese.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 2206; COL4A4; Simple; p.Pro1096Ser (c.3286C>T); Zygosity=Heterozygous (PubMed=35076391).
  • Mutation; HGNC; 2207; COL4A5; Simple; p.Gly1232Asp (c.3695G>A); Zygosity=Hemizygous (PubMed=35076391).
Disease Alport syndrome (NCIt: C34842)
Alport syndrome (ORDO: Orphanet_63)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_LF15 ! HPSI0516i-yist_1
Sex of cell Male
Age at sampling 22Y
Category Induced pluripotent stem cell

PubMed=35076391; DOI=10.7554/eLife.73486
Morais M.R.P.T., Tian P.-Y., Lawless C., Murtuza-Baker S., Hopkinson L., Woods S., Mironov A., Long D.A., Gale D.P., Zorn T.M.T., Kimber S.J., Zent R., Lennon R.
Kidney organoids recapitulate human basement membrane assembly in health and disease.
eLife 11:e73486.1-e73486.30(2022)

Cell line collections (Providers) ECACC; 77650724
Cell line databases/resources HipSci; HPSI0516i-yist_3
hPSCreg; WTSIi623-A
Biological sample resources BioSamples; SAMEA4673668
Encyclopedic resources Wikidata; Q54890987
Entry history
Entry creation22-Aug-2017
Last entry update29-Jun-2023
Version number10