| Cell line name |
SW48 HRAS (G12V/+) |
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| Synonyms |
HRAS (G12V/+) SW48 |
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| Accession |
CVCL_LC87 |
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| Resource Identification Initiative |
To cite this cell line use: SW48 HRAS (G12V/+) (RRID:CVCL_LC87) |
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| Comments |
Population: Caucasian.
Characteristics: Heterozygous knockin of a HRAS activating mutation.
Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
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| Sequence variations |
- Mutation; HGNC; HGNC:173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Arg2714Cys (c.8140C>T); ClinVar=VCV000231255; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; HGNC:914; B2M; Simple; p.Ser14fs*29 (c.41_44delCTCT); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:914; B2M; Simple; p.Glu67fs (c.200delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser33Tyr (c.98C>A); ClinVar=VCV000017577; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:5173; HRAS; Simple_edited; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Heterozygous; Note=By method not specified (Horizon_Discovery=HD+103-034).
- Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Colon adenocarcinoma (NCIt: C4349) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_1724 (SW48) |
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| Sex of cell |
Female |
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| Age at sampling |
83Y |
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| Category |
Cancer cell line |
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| Cross-references |
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| Cell line collections (Providers) |
Horizon_Discovery; HD+103-034
|
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| Cell line databases/resources |
cancercelllines; CVCL_LC87
|
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| Encyclopedic resources |
Wikidata; Q54971123
|
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| Entry history |
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| Entry creation | 22-Aug-2017 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 14 |
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