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Cellosaurus PeTa (CVCL_LC73)

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Cell line name PeTa
Synonyms PETA
Accession CVCL_LC73
Resource Identification Initiative To cite this cell line use: PeTa (RRID:CVCL_LC73)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 2-3 days (PubMed=30873613).
Transformant: NCBI_TaxID; 493803; Merkel cell polyomavirus (MCPyV).
Omics: Proteomics; Quantitative.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Disease Merkel cell carcinoma (NCIt: C9231)
Cutaneous neuroendocrine carcinoma (ORDO: Orphanet_79140)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 65Y
Category Cancer cell line
STR profile Source(s): PubMed=30873613

Markers:
AmelogeninX,Y
CSF1PO11,12
D3S135814,15
D5S81812
D7S8209,13
D8S117914,15
D13S3178,12
D16S53911,12
D18S5115,16
D21S1130.2,32
FGA19,21
Penta D11,13
Penta E10,16
TH016,9
TPOX8
vWA15,17

Run an STR similarity search on this cell line
Publications

PubMed=23563200; DOI=10.1038/jid.2013.169
Roland Houben, Christina Dreher, Sabrina Angermeyer, Andreas Borst, Jochen Sven Utikal, Sebastian Haferkamp, Wiebke K. Peitsch, David Schrama, Sonja Hesbacher;
Mechanisms of p53 restriction in Merkel cell carcinoma cells are independent of the Merkel cell polyoma virus T antigens.
J. Invest. Dermatol. 133:2453-2460(2013)

PubMed=27121059; DOI=10.18632/oncotarget.8793; PMCID=PMC5078066
Sonja Hesbacher, Lisa Pfitzer, Katharina Wiedorfer, Sabrina Angermeyer, Andreas Borst, Sebastian Haferkamp, Claus-Jurgen Scholz, Marion Wobser, David Schrama, Roland Houben;
RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells.
Oncotarget 7:32956-32968(2016)

PubMed=30873613; DOI=10.1002/ijc.32280
David Schrama, Eva-Maria Sarosi, Christian Adam, Cathrin Ritter, Ulrike Kaemmerer, Eva Klopocki, Eva-Maria Konig, Jochen Sven Utikal, Jurgen C. Becker, Roland Houben;
Characterization of six Merkel cell polyomavirus-positive Merkel cell carcinoma cell lines: integration pattern suggest that large T antigen truncating events occur before or during integration.
Int. J. Cancer 145:1020-1032(2019)

PubMed=31889939; DOI=10.1186/s12014-019-9263-z; PMCID=PMC6921584
Ulana Kotowski, Boban M. Erovic, Julia Schnoll, Victoria Stanek, Stefan Janik, Martin Steurer, Goran Mitulovic;
Quantitative proteome analysis of Merkel cell carcinoma cell lines using SILAC.
Clin. Proteomics 16:42.1-42.13(2019)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01848
DepMap; ACH-001170
Encyclopedic resources Wikidata; Q54947234
Proteomic databases PRIDE; PXD008181
Entry history
Entry creation22-Aug-2017
Last entry update10-Apr-2025
Version number8