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Cellosaurus AlDo (CVCL_LC71)

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Cell line name AlDo
Accession CVCL_LC71
Resource Identification Initiative To cite this cell line use: AlDo (RRID:CVCL_LC71)
Comments Doubling time: 7 days (PubMed=30873613).
Transformant: NCBI_TaxID; 493803; Merkel cell polyomavirus (MCPyV).
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Back, skin; UBERON=UBERON_0001068.
Disease Merkel cell carcinoma (NCIt: C9231)
Cutaneous neuroendocrine carcinoma (ORDO: Orphanet_79140)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): PubMed=30873613

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135815.2,17
D5S81810
D7S82010,12
D8S117913,14
D13S31711
D16S53911,12
D18S5112,17
D21S1130.2,33.2
FGA21,25
Penta D8,9
Penta E5,17
TH017,8
TPOX10,11
vWA16,19

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Publications

PubMed=23563200; DOI=10.1038/jid.2013.169
Roland Houben, Christina Dreher, Sabrina Angermeyer, Andreas Borst, Jochen Sven Utikal, Sebastian Haferkamp, Wiebke K. Peitsch, David Schrama, Sonja Hesbacher;
Mechanisms of p53 restriction in Merkel cell carcinoma cells are independent of the Merkel cell polyoma virus T antigens.
J. Invest. Dermatol. 133:2453-2460(2013)

PubMed=30873613; DOI=10.1002/ijc.32280
David Schrama, Eva-Maria Sarosi, Christian Adam, Cathrin Ritter, Ulrike Kaemmerer, Eva Klopocki, Eva-Maria Konig, Jochen Sven Utikal, Jurgen C. Becker, Roland Houben;
Characterization of six Merkel cell polyomavirus-positive Merkel cell carcinoma cell lines: integration pattern suggest that large T antigen truncating events occur before or during integration.
Int. J. Cancer 145:1020-1032(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_LC71
Encyclopedic resources Wikidata; Q54749156
Gene expression databases GEO; GSM1904842
Polymorphism and mutation databases Progenetix; CVCL_LC71
Entry history
Entry creation22-Aug-2017
Last entry update10-Apr-2025
Version number9