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Cellosaurus ValiScreen human CRTH2 (CVCL_LC58)

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Cell line name ValiScreen human CRTH2
Synonyms ValiScreen human prostanoid receptor DP2; CHO-CRTH2; hCRTH2-CHO
Accession CVCL_LC58
Resource Identification Initiative To cite this cell line use: ValiScreen human CRTH2 (RRID:CVCL_LC58)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4502; PTGDR2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=21916510; DOI=10.1021/jm200866y
Stefano Crosignani, Adeline Pretre, Catherine Jorand-Lebrun, Gaele Fraboulet, Jeyaprakashnarayanan Seenisamy, John Kallikat Augustine, Marc Missotten, Yves Humbert, Christophe Cleva, Nada Abla, Hamina Daff ...Show all 21 authors... , Olivier Schott, Manfred Schneider, Fabienne Burgat-Charvillon, Delphine Rivron, Ingrid Hamernig, Jean-Francois Arrighi, Marilene Gaudet, Simone C. Zimmerli, Pierre Juillard, Zoe Johnson; Show fewer authors
Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.
J. Med. Chem. 54:7299-7317(2011)

Cross-references
Cell line collections (Providers) Revvity/PerkinElmer; ES-561-C
Encyclopedic resources Wikidata; Q54992922
Entry history
Entry creation22-Aug-2017
Last entry update27-Nov-2025
Version number12