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Cellosaurus UOK276 (CVCL_LC28)

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Cell line name UOK276
Accession CVCL_LC28
Resource Identification Initiative To cite this cell line use: UOK276 (RRID:CVCL_LC28)
Comments Doubling time: ~24 hours (Direct_author_submission).
Omics: Genomics; Mitochondrial genome sequencing.
Miscellaneous: Doubling time from personal communication of Yang, You-Feng.
Derived from site: Metastatic; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Tyr (c.577C>T); ClinVar=VCV000230256; Zygosity=Homozygous (PubMed=28736828).
  • Mutation; HGNC; HGNC:20456; TRAF7; Simple; p.Pro22_Thr25del; Zygosity=Homozygous; Note=Heterozygous mutation in germline of patient (PubMed=28736828).
Disease Chromophobe renal cell carcinoma (NCIt: C4146)
Chromophobe renal cell carcinoma (ORDO: Orphanet_319303)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
STR profile Source(s): PubMed=28736828

Markers:
AmelogeninX,Y
CSF1PO11
D3S135815
D5S81811
D7S82011
D8S117910,12
D13S31711
D16S53910
D18S5113
D21S1131
FGA20
Penta D10
Penta E10
TH019.3
TPOX8
vWA16

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Publications

PubMed=28736828; DOI=10.1002/gcc.22476; PMCID=PMC5561006
You-Feng Yang, Cathy D. Vocke, Christopher J. Ricketts, Darmood Wei, Hesed Maria Padilla-Nash, Martin Lang, Carole Sourbier, Jonathan Keith Killian, Shawna Lee Boyle, Robert A. Worrell, Paul S. Meltzer ...Show all 15 authors... , Thomas Ried, Maria J. Merino, Adam R. Metwalli, William Marston Linehan; Show fewer authors
Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276).
Genes Chromosomes Cancer 56:719-729(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_LC28
Encyclopedic resources Wikidata; Q54991422
Entry history
Entry creation22-Aug-2017
Last entry update10-Apr-2025
Version number12