Cellosaurus logo
expasy logo

Cellosaurus SpR (CVCL_L986)

[Text version]
Cell line name SpR
Synonyms SPR; SP
Accession CVCL_L986
Resource Identification Initiative To cite this cell line use: SpR (RRID:CVCL_L986)
Comments Group: Non-human primate cell line.
Problematic cell line: Misidentified/contaminated. Originally thought to be of human origin but found to derive from Aotus trivirgatus OMK-210 (PubMed=7192801; PubMed=12592342; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00088.
Anecdotal: Part of a set of 4 cell lines that were fraudulently stated to originate from Hodgkin lymphoma (PubMed=265539).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Aotus trivirgatus (Three-striped night monkey) (Douroucouli) (NCBI Taxonomy: 9505)
Hierarchy Parent: CVCL_L983 (OMK-210)
Sex of cell Female
Category Undefined cell line type
Web pages https://www.nytimes.com/1981/01/22/us/cells-in-disease-study-said-to-come-from-monkeys.html

PubMed=68093; DOI=10.1084/jem.145.6.1484
Long J.C., Zamecnik P.C., Aisenberg A.C., Atkins L.
Tissue culture studies in Hodgkin's disease: morphologic, cytogenetic, cell surface, and enzymatic properties of cultures derived from splenic tumors.
J. Exp. Med. 145:1484-1500(1977)

PubMed=265539; DOI=10.1073/pnas.74.2.754
Zamecnik P.C., Long J.C.
Growth of cultured cells from patients with Hodgkin's disease and transplantation into nude mice.
Proc. Natl. Acad. Sci. U.S.A. 74:754-758(1977)

PubMed=7005696; DOI=10.1038/289227a0
Dickson D.
Contaminated cell lines.
Nature 289:227-227(1981)

PubMed=7192801; DOI=10.1038/289228a0
Harris N.L., Gang D.L., Quay S.C., Poppema S., Zamecnik P.C., Nelson-Rees W.A., O'Brien S.J.
Contamination of Hodgkin's disease cell cultures.
Nature 289:228-230(1981)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=29533902; DOI=10.1515/hsz-2017-0321
Drexler H.G., Pommerenke C., Eberth S., Nagel S.
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.
Biol. Chem. 399:511-523(2018)

Biological sample resources BioSample; SAMN03151878
Encyclopedic resources Wikidata; Q54955583
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number18