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Cellosaurus GM02504 (CVCL_L976)

[Text version]
Cell line name GM02504
Synonyms GM-2504; GM 2504; GM02504H; GM00258; GM-258; GM258
Accession CVCL_L976
Resource Identification Initiative To cite this cell line use: GM02504 (RRID:CVCL_L976)
Comments Population: African American.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_EJ80 (WISCi006-A)
Sex of cell Male
Age at sampling 1M
Category Finite cell line
Publications

DOI=10.5962/bhl.title.4090
Lewis Lemon Coriell, Arthur E. Greene;
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 4th edition. October 1977.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda; USA (1977)

PubMed=694721; DOI=10.1007/BF01542843
Yuan-Tsong Chen, Thomas E. Worthy, Robert Schild Krooth;
Evidence for a striking increase in acetylcholinesterase activity in cultured human fibroblasts which are trisomic for chromosome two.
Somatic Cell Genet. 4:265-298(1978)

PubMed=291901; DOI=10.1073/pnas.76.10.4817; PMCID=PMC413028
Sohan L. Gupta, Berish Y. Rubin, Sandra L. Holmes;
Interferon action: induction of specific proteins in mouse and human cells by homologous interferons.
Proc. Natl. Acad. Sci. U.S.A. 76:4817-4821(1979)

PubMed=6159644; DOI=10.1073/pnas.77.9.5341; PMCID=PMC350054
Roy H.L. Pang, Teresa G. Hayes, Jan T. Vilcek;
Le interferon mRNA from human fibroblasts.
Proc. Natl. Acad. Sci. U.S.A. 77:5341-5345(1980)

PubMed=6160588; DOI=10.1073/pnas.77.10.5938; PMCID=PMC350187
Lulu A. Pickering, Lee H. Kronenberg, William E. Stewart 2nd;
Spontaneous production of human interferon.
Proc. Natl. Acad. Sci. U.S.A. 77:5938-5942(1980)

PubMed=7299037; DOI=10.1016/0165-022X(81)90016-6
Sandro Sorbi, John Paul Blass;
Spectrophotometric measurement of pyruvate dehydrogenase complex activity in cultured human fibroblasts.
J. Biochem. Biophys. Methods 5:169-176(1981)

PubMed=6179471; DOI=10.1016/0166-3542(82)90029-8
Marc De Ley, Alfons Billiau;
Responsiveness of human cells trisomic for chromosome 21 to the antiviral action of human immune interferon.
Antiviral Res. 2:97-102(1982)

CLPUB00447
Richard A. Mulivor, Sharon F. Suchy;
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992)

PubMed=17668376; DOI=10.1086/519248; PMCID=PMC1950802
Paola Prandini, Samuel Deutsch, Robert Lyle, Maryline Gagnebin, Celine Delucinge-Vivier, Mauro Delorenzi, Corinne Gehrig, Patrick Descombes, Stephanie L. Sherman, Franca Dagna-Bricarelli, Chiara Baldo ...Show all 14 authors... , Antonio Novelli, Bruno Dallapiccola, Stylianos E. Antonarakis; Show fewer authors
Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance.
Am. J. Hum. Genet. 81:252-263(2007)

PubMed=23716668; DOI=10.1073/pnas.1216575110; PMCID=PMC3683748
Jason P. Weick, Dustie L. Held, George Fred Bonadurer 3rd, Matthew E. Doers, Yan Liu, Chelsie Maguire, Aaron Clark, Joshua A. Knackert, Katharine Molinarolo, Michael T. Musser, Lin Yao ...Show all 16 authors... , Ying-Nan Yin, Jian-Feng Lu, Xiao-Qing Zhang, Su-Chun Zhang, Anita Bhattacharyya; Show fewer authors
Deficits in human trisomy 21 iPSCs and neurons.
Proc. Natl. Acad. Sci. U.S.A. 110:9962-9967(2013)

Cross-references
Cell line collections (Providers) Coriell; GM00258 - Discontinued
Coriell; GM02504
Cell line databases/resources CLO; CLO_0033251
Encyclopedic resources Wikidata; Q54837524
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number20