| Cell line name |
PC-1.0 |
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| Synonyms |
PC-1-0; PC1.0 |
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| Accession |
CVCL_L901 |
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| Resource Identification Initiative |
To cite this cell line use: PC-1.0 (RRID:CVCL_L901) |
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| Comments |
Transformant: ChEBI; CHEBI_131518; N,N-bis(2-hydroxypropyl)nitrosamine (Diisopropanolnitrosamine; DIPN; N-nitrosobis(2-hydroxypropyl)amine).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264. |
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| Sequence variations |
- Mutation; UniProtKB; A0A1U7QTX5; Kras; Simple; p.Gly12Asp (c.35G>A); Zygosity=Unspecified (PubMed=2173932).
|
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| Disease |
Hamster pancreatic ductal adenocarcinoma (NCIt: C133090) |
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| Species of origin |
Mesocricetus auratus (Golden hamster)
(NCBI Taxonomy: 10036) |
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| Hierarchy |
Parent: CVCL_L900 (PC-1 [Hamster]) |
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| Sex of cell |
Male |
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| Age at sampling |
8W |
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| Category |
Cancer cell line |
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| Publications | PubMed=2173932; DOI=10.1002/mc.2940030510
Hideki Fujii, Hiroshi Egami, William G. Chaney, Parviz M. Pour, Jill Pelling;
Pancreatic ductal adenocarcinomas induced in Syrian hamsters by N-nitrosobis(2-oxopropyl)amine contain a c-Ki-ras oncogene with a point-mutated codon 12.
Mol. Carcinog. 3:296-301(1990) PubMed=1530768
Krishnanand D. Kumble, Masahiko Hirota, Parviz M. Pour, Jamboor K. Vishwanatha;
Enhanced levels of annexins in pancreatic carcinoma cells of Syrian hamsters and their intrapancreatic allografts.
Cancer Res. 52:163-167(1992) PubMed=8382114; DOI=10.1093/carcin/14.2.259
Masahiko Hirota, Hiroshi Egami, Stefano Corra, Hideki Fujii, William G. Chaney, Angie Rizzino, Parviz M. Pour;
Production of scatter factor-like activity by a nitrosamine-induced pancreatic cancer cell line.
Carcinogenesis 14:259-264(1993) PubMed=8863680; PMCID=PMC1865186
Nadina Erill, Miriam Cuatrecasas, Francisco J. Sancho, Antonio Farre, Parviz M. Pour, Felix Lluis, Gabriel Capella;
K-ras and p53 mutations in hamster pancreatic ductal adenocarcinomas and cell lines.
Am. J. Pathol. 149:1333-1339(1996) |
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| Cross-references |
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| Anatomy/cell type resources |
BTO; BTO_0002746
|
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| Encyclopedic resources |
Wikidata; Q54938385
|
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| Entry history |
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| Entry creation | 06-May-2013 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 14 |
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