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Cellosaurus 1Cc8 (CVCL_L893)

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Cell line name 1Cc8
Synonyms 1CC8; SCC-1CC8; SC8
Accession CVCL_L893
Resource Identification Initiative To cite this cell line use: 1Cc8 (RRID:CVCL_L893)
Comments Population: Caucasian.
Selected for resistance to: DrugBank; DB00002; Cetuximab (Erbitux).
Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
Disease Floor of mouth squamous cell carcinoma (NCIt: C4041)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7707 (UM-SCC-1)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=18297114; DOI=10.1038/onc.2008.19; PMCID=PMC2903615
Deric L. Wheeler, Shyh-Min Huang, Timothy J. Kruser, Meghan M. Nechrebecki, Eric Anthony Armstrong, Sergio Benavente, Vinai Gondi, Kun-Tai Hsu, Paul M. Harari;
Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members.
Oncogene 27:3944-3956(2008)

Cross-references
Encyclopedic resources Wikidata; Q54582811
Entry history
Entry creation06-May-2013
Last entry update19-Dec-2024
Version number20