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Cellosaurus MM46 [Human mesothelioma] (CVCL_L793)

[Text version]
Cell line name MM46 [Human mesothelioma]
Synonyms MM46-P
Accession CVCL_L793
Resource Identification Initiative To cite this cell line use: MM46 [Human mesothelioma] (RRID:CVCL_L793)
Comments Population: Japanese.
Doubling time: 11.5 +- 0.5 hours (PubMed=21205078).
Transformant: ChEBI; CHEBI_46661; Asbestos.
Omics: Genomics; Whole exome sequencing.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
Disease Pleural sarcomatoid mesothelioma (NCIt: C45663)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=21205078; DOI=10.1111/j.1349-7006.2010.01827.x; PMCID=PMC11158380
Ayuko Sato, Ikuko Torii, Li-Hua Tao, Misa Song, Nobuyuki Kondo, Yoshie Yoshikawa, Tomoko Hashimoto-Tamaoki, Seiki Hasegawa, Takashi Nakano, Tohru Tsujimura;
Establishment of a cell line from a Japanese patient useful for generating an in vivo model of malignant pleural mesothelioma.
Cancer Sci. 102:648-655(2011)

PubMed=24916674; DOI=10.1002/ijc.29015
Yoshie Yoshikawa, Ayuko Sato, Tohru Tsujimura, Takemi Otsuki, Kazuya Fukuoka, Seiki Hasegawa, Takashi Nakano, Tomoko Hashimoto-Tamaoki;
Biallelic germline and somatic mutations in malignant mesothelioma: multiple mutations in transcription regulators including mSWI/SNF genes.
Int. J. Cancer 136:560-571(2015)

Cross-references
Encyclopedic resources Wikidata; Q54906138
Gene expression databases GEO; GSM1275978
GEO; GSM1275994
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number13