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Cellosaurus 3Y1tsD123 (CVCL_L735)

[Text version]

Cell line name 3Y1tsD123
Synonyms 3Y1 tsD123
Accession CVCL_L735
Resource Identification Initiative To cite this cell line use: 3Y1tsD123 (RRID:CVCL_L735)
Comments Characteristics: Temperature sensitive for proliferation. Defective at 38.5 Celsius (selection temperature) in undergoing the transition from quiescent to proliferating state.
Selected for resistance to: ChEBI; CHEBI:472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; BrdU; BUdR).
Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from sampling site: Whole embryo. Cell type=Fibroblast.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344.
Hierarchy Parent: CVCL_E147 (3Y1-B clone 1-6)
Sex of cell Female
Age at sampling Embryo
Category Transformed cell line
Publications

PubMed=6583851; DOI=10.1007/BF01534469
Ohno K., Okuda A., Ohtsu M., Kimura G.
Genetic analysis of control of proliferation in fibroblastic cells in culture. I. Isolation and characterization of mutants temperature-sensitive for proliferation or survival of untransformed diploid rat cell line 3Y1.
Somat. Cell Mol. Genet. 10:17-28(1984)

PubMed=2553277; DOI=10.1247/csf.14.375
Matsuzaki A., Ohno K., Ohtsu M., Kimura G.
Functional rescue of temperature-sensitive defects in the cell-cycle mutants of rat 3Y1 fibroblasts by the small t-antigen deletion mutant of simian virus 40.
Cell Struct. Funct. 14:375-382(1989)

Cross-references
Cell line collections RCB; RCB0313
Encyclopedic resources Wikidata; Q54602822
Entry history
Entry creation06-May-2013
Last entry update17-Mar-2022
Version number7