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Cellosaurus AG04059 (CVCL_L623)

[Text version]
Cell line name AG04059
Synonyms AG-4059; AG 4059; AG04059B; GRC#0179
Accession CVCL_L623
Resource Identification Initiative To cite this cell line use: AG04059 (RRID:CVCL_L623)
Comments Part of: Baltimore Longitudinal Study of Aging (BLSA) cell line collection.
Population: Caucasian.
Doubling time: Slow growth (Coriell=AG04059).
Karyotypic information: 46,XY [94%]; 45,X [6%] (Coriell=AG04059).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 96Y
Category Finite cell line
Publications

PubMed=7307581; DOI=10.1159/000131624
Edward L. Schneider, Robert Monticone, James R. Smith, Karen I. Braunschweiger, Thomas W. Roberts;
Skin fibroblast cultures derived from members of the Baltimore longitudinal study: a new resource for studies of cellular aging.
Cytogenet. Cell Genet. 31:40-46(1981)

PubMed=7176709; DOI=10.1016/0047-6374(82)90061-6
Trygve O. Tollefsbol, M. Rebecca Zaun, Robert W. Gracy;
Increased lability of triosephosphate isomerase in progeria and Werner's syndrome fibroblasts.
Mech. Ageing Dev. 20:93-101(1982)

PubMed=6223188; DOI=10.1016/0047-6374(83)90071-4
M. Lynne Chapman, M. Rebecca Zaun, Robert W. Gracy;
Changes in NAD levels in human lymphocytes and fibroblasts during aging and in premature aging syndromes.
Mech. Ageing Dev. 21:157-167(1983)

PubMed=6538202; DOI=10.1083/jcb.98.3.1133; PMCID=PMC2113122
Bruno Azzarone, Horacio Guillermo Suarez, Maria Cristina Mingari, Lorenzo Moretta, Anthony Stephen Fauci;
4F2 monoclonal antibody recognizes a surface antigen on spread human fibroblasts of embryonic but not of adult origin.
J. Cell Biol. 98:1133-1137(1984)

PubMed=3374507; DOI=10.1016/0027-5107(88)90211-4
Bruno Azzarone, Christine Chaponnier, Patricia Krief, Marc M. Mareel, Horacio Guillermo Suarez, Alvaro Macieira-Coelho;
Human fibroblasts from cancer patients: lifespan and transformed phenotype in vitro and role of mesenchyme in vivo.
Mutat. Res. 199:313-325(1988)

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=10741968; DOI=10.1126/science.287.5462.2486
Danith H. Ly, David J. Lockhart, Richard Alan Lerner, Peter G. Schultz;
Mitotic misregulation and human aging.
Science 287:2486-2492(2000)

PubMed=30567591; DOI=10.1186/s13059-018-1599-6; PMCID=PMC6300908
Jason G. Fleischer, Roberta Schulte, Hsiao H. Tsai, Swati Tyagi, Arkaitz Ibarra, Maxim N. Shokhirev, Ling Huang, Martin W. Hetzer, Saket Navlakha;
Predicting age from the transcriptome of human dermal fibroblasts.
Genome Biol. 19:221.1-221.8(2018)

Cross-references
Cell line collections (Providers) Coriell; AG04059
Cell line databases/resources CLO; CLO_0034766
Encyclopedic resources Wikidata; Q54609911
Gene expression databases GEO; GSM3124624
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number16