Cellosaurus cell line H21F8-1 (CVCL

Cellosaurus H21F8-1 (CVCL_L519)

Cross-references
Cell line name	H21F8-1
Synonyms	1F8
Accession	CVCL_L519
Resource Identification Initiative	To cite this cell line use: H21F8-1 (RRID:CVCL_L519)
Comments	Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8018. Monoclonal antibody isotype: IgM. Monoclonal antibody target: Hepatitis B virus HBsAg.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy	Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category	Hybridoma
Publications	Patent=US4271145 Jack Raymond Wands, Vincent Richard Zurawski Jr.; Process for producing antibodies to hepatitis virus and cell lines therefor. Patent number US4271145, 02-Jun-1981 PubMed=6940137; DOI=10.1073/pnas.78.2.1214; PMCID=PMC319978 Jack Raymond Wands, Rolf I. Carlson, Hubert Jacob Paul Schoemaker, Kurt Julius Isselbacher, Vincent Richard Zurawski Jr.; Immunodiagnosis of hepatitis B with high-affinity IgM monoclonal antibodies. Proc. Natl. Acad. Sci. U.S.A. 78:1214-1218(1981) Patent=US4870026 Jack Raymond Wands, David A. Shafritz; Non-A, non-B hepatitis, virus, methods of identification purification, characterization, diagnosis and immunization. Patent number US4870026, 26-Sep-1989 PubMed=18600747; DOI=10.1002/bit.260380209 James D. Michaels, Jonathan F. Petersen, Larry V. McIntire, Eleftherios Terry Papoutsakis; Protection mechanisms of freely suspended animal cells (CRL 8018) from fluid-mechanical injury. Viscometric and bioreactor studies using serum, pluronic F68 and polyethylene glycol. Biotechnol. Bioeng. 38:169-180(1991)
Cell line collections (Providers)	ATCC; CRL-8018 - Discontinued BCRC; 60234
Cell line databases/resources	CLO; CLO_0003589
Encyclopedic resources	Wikidata; Q54872016
Entry history
Entry creation	06-May-2013
Last entry update	14-Aug-2025
Version number	9