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Cellosaurus NUGC-3/5-FU/L (CVCL_L502)

[Text version]
Cell line name NUGC-3/5-FU/L
Synonyms NUGC-3/5FU/L; NUGC-3/5-FU; NUGC-3/5FU
Accession CVCL_L502
Resource Identification Initiative To cite this cell line use: NUGC-3/5-FU/L (RRID:CVCL_L502)
Comments Part of: JFCR45 cancer cell line panel.
Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU).
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Brachialis muscle; UBERON=UBERON_0001506.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Unspecified (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1612 (NUGC-3)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=8609072; DOI=10.1111/j.1349-7006.1996.tb03161.x; PMCID=PMC5921054
Makoto Inaba, Junko Mitsuhashi, Hiroko Sawada, Naoko Miike, Yoshinori Naoe, Aiko Daimon, Kazuhisa Koizumi, Hiroaki Tsujimoto, Masakazu Fukushima;
Reduced activity of anabolizing enzymes in 5-fluorouracil-resistant human stomach cancer cells.
Jpn. J. Cancer Res. 87:212-220(1996)

PubMed=10359051; DOI=10.1111/j.1349-7006.1999.tb00754.x; PMCID=PMC5926061
Makoto Inaba, Hiroko Sawada, Akiko Sadata, Hirofumi Hamada;
Circumvention of 5-fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction.
Jpn. J. Cancer Res. 90:349-354(1999)

PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234
Noriyuki Nakatsu, Yoko Yoshida, Kanami Yamazaki, Tomoki Nakamura, Shingo Dan, Yasuhisa Fukui, Takao Yamori;
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.
Mol. Cancer Ther. 4:399-412(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_L502
Encyclopedic resources Wikidata; Q54931162
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number19