Cellosaurus logo
expasy logo

Cellosaurus P2UR/K-562 (CVCL_L434)

[Text version]
Cell line name P2UR/K-562
Synonyms P2URK562
Accession CVCL_L434
Resource Identification Initiative To cite this cell line use: P2UR/K-562 (RRID:CVCL_L434)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:8541; P2RY2.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (DepMap=ACH-002061).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): RCB=RCB1197

Markers:
AmelogeninX
CSF1PO9,10
D5S81811,12
D7S8209,11
D13S3178
D16S53911,12
TH019.3
TPOX8,9
vWA16

Run an STR similarity search on this cell line
Cross-references
Cell line collections (Providers) RCB; RCB1197
Cell line databases/resources CLO; CLO_0050120
DepMap; ACH-002061
Encyclopedic resources Wikidata; Q54937240
Entry history
Entry creation06-May-2013
Last entry update19-Dec-2024
Version number22