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Cellosaurus Marisco (CVCL_L363)

[Text version]
Cell line name Marisco
Synonyms Moresco
Accession CVCL_L363
Resource Identification Initiative To cite this cell line use: Marisco (RRID:CVCL_L363)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 22.1 hours (PubMed=22916246); 22 hours (PubMed=27257868).
Omics: Deep exome analysis.
Omics: Genome sequenced.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; VGNC; 43959; NRAS; Simple; p.Gln61His (c.183A>C); Zygosity=Heterozygous (PubMed=31175136).
  • Mutation; VGNC; 49609; RAC1; Simple; p.Pro29Thr (c.85C>A); Zygosity=Heterozygous (PubMed=31175136).
Disease Canine osteosarcoma (NCIt: C120045)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Greyhound.
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=27197945; PubMed=31175136

Dog FHC2010227
Dog FHC2054156
Dog FHC2079271
Dog PEZ1107
Dog PEZ12263,297
Dog PEZ20200
Dog PEZ3119,131
Dog PEZ5103
Dog PEZ6172,183
Dog PEZ8236

Run an STR similarity search on this cell line

PubMed=21552385; DOI=10.7150/jca.2.262
Legare M.E., Bush J., Ashley A.K., Kato T., Hanneman W.H.
Cellular and phenotypic characterization of canine osteosarcoma cell lines.
J. Cancer 2:262-270(2011)

PubMed=21908323; DOI=10.1177/1040638711408064
O'Donoghue L.E., Rivest J.P., Duval D.L.
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

PubMed=22916246; DOI=10.1371/journal.pone.0043355
Maeda J., Yurkon C.R., Fujisawa H., Kaneko M., Genet S.C., Roybal E.J., Rota G.W., Saffer E.R., Rose B.J., Hanneman W.H., Thamm D.H., Kato T.A.
Genomic instability and telomere fusion of canine osteosarcoma cells.
PLoS ONE 7:E43355-E43355(2012)

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=27197945; DOI=10.1111/vco.12192
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

PubMed=36099278; DOI=10.1371/journal.pone.0274383
Megquier K., Turner-Maier J., Morrill K., Li X., Johnson J., Karlsson E.K., London C.A., Gardner H.L.
The genomic landscape of canine osteosarcoma cell lines reveals conserved structural complexity and pathway alterations.
PLoS ONE 17:E0274383-E0274383(2022)

Anatomy/cell type resources BTO; BTO:0005359
Encyclopedic resources Wikidata; Q54904031
Gene expression databases GEO; GSM1974794
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number17