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Cellosaurus Marisco (CVCL_L363)

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Cell line name Marisco
Synonyms Moresco
Accession CVCL_L363
Resource Identification Initiative To cite this cell line use: Marisco (RRID:CVCL_L363)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 22.1 hours (PubMed=22916246); 22 hours (PubMed=27257868).
Omics: Genomics; Whole exome sequencing.
Omics: Genomics; Whole genome sequencing.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; VGNC; VGNC:43959; NRAS; Simple; p.Gln61His (c.183A>C); Zygosity=Heterozygous (PubMed=31175136).
  • Mutation; VGNC; VGNC:49609; RAC1; Simple; p.Pro29Thr (c.85C>A); Zygosity=Heterozygous (PubMed=31175136).
Disease Canine osteosarcoma (NCIt: C120045)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Greyhound; VBO=VBO_0200638.
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=27197945; PubMed=31175136

Markers:
Dog FHC2010227
Dog FHC2054156
Dog FHC2079271
Dog PEZ1107
Dog PEZ12263,297
Dog PEZ20200
Dog PEZ3119,131
Dog PEZ5103
Dog PEZ6172,183
Dog PEZ8236

Run an STR similarity search on this cell line
Publications

PubMed=21552385; DOI=10.7150/jca.2.262; PMCID=PMC3088864
Marie E. Legare, Jamie Bush, Amanda K. Ashley, Taka Kato, William H. Hanneman;
Cellular and phenotypic characterization of canine osteosarcoma cell lines.
J. Cancer 2:262-270(2011)

PubMed=21908323; DOI=10.1177/1040638711408064
Liza E. O'Donoghue, Jason P. Rivest, Dawn L. Duval;
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

PubMed=22916246; DOI=10.1371/journal.pone.0043355; PMCID=PMC3420908
Junko Maeda, Charles R. Yurkon, Hiroshi Fujisawa, Masami Kaneko, Stefan C. Genet, Erica J. Roybal, Garrett Wayne Rota, Ethan R. Saffer, Barbara J. Rose, William H. Hanneman, Douglas H. Thamm, Takamitsu A. Kato;
Genomic instability and telomere fusion of canine osteosarcoma cells.
PLoS ONE 7:e43355.1-e43355.12(2012)

PubMed=27257868; DOI=10.1371/journal.pone.0156689; PMCID=PMC4892608
Junko Maeda, Coral Eva Froning, Colleen A. Brents, Barbara J. Rose, Douglas H. Thamm, Takamitsu A. Kato;
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:e0156689.1-e0156689.18(2016)

PubMed=27197945; DOI=10.1111/vco.12192; PMCID=PMC5656225
Jared S. Fowles, Deanna D. Dailey, Daniel L. Gustafson, Douglas H. Thamm, Dawn L. Duval;
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346; PMCID=PMC6679748
Sunetra Das, Rupa Idate, Kathryn E. Cronise, Daniel L. Gustafson, Dawn L. Duval;
Identifying candidate druggable targets in canine cancer cell lines using whole-exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

PubMed=36099278; DOI=10.1371/journal.pone.0274383; PMCID=PMC9469990
Kate Megquier, Jason Turner-Maier, Kathleen Morrill, Xue Li, Jeremy Johnson, Elinor K. Karlsson, Cheryl A. London, Heather L. Gardner;
The genomic landscape of canine osteosarcoma cell lines reveals conserved structural complexity and pathway alterations.
PLoS ONE 17:e0274383.1-e0274383.18(2022)

Cross-references
Anatomy/cell type resources BTO; BTO_0005359
Encyclopedic resources Wikidata; Q54904031
Gene expression databases GEO; GSM1974794
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number20