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Cellosaurus CMT-U27 (CVCL_L335)

[Text version]
Cell line name CMT-U27
Synonyms Cell line 27; #27; CMT5
Accession CVCL_L335
Resource Identification Initiative To cite this cell line use: CMT-U27 (RRID:CVCL_L335)
Comments Doubling time: ~48 hours (PubMed=1375928); 54.7 hours (PubMed=20453304).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Canine mammary carcinoma (NCIt: C124249)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Poodle; VBO=VBO_0201048.
Sex of cell Female
Age at sampling 14Y
Category Cancer cell line
Publications

PubMed=1375928; DOI=10.1007/BF02877054
Hellmen E.
Characterization of four in vitro established canine mammary carcinoma and one atypical benign mixed tumor cell lines.
In Vitro Cell. Dev. Biol. Anim. 28:309-319(1992)

PubMed=9042250
van Leeuwen I.S., Hellmen E., Cornelisse C.J., van der Burg B., Rutteman G.R.
p53 mutations in mammary tumor cell lines and corresponding tumor tissues in the dog.
Anticancer Res. 16:3737-3744(1996)

PubMed=19609018
Krol M., Pawlowski K.M., Skierski J.S., Rao N.A.S., Hellmen E., Mol J.A., Motyl T.
Transcriptomic profile of two canine mammary cancer cell lines with different proliferative and anti-apoptotic potential.
J. Physiol. Pharmacol. 60 Suppl. 1:95-106(2009)

PubMed=20453304; DOI=10.1007/BF03195725
Krol M., Pawlowski K.M., Skierski J.S., Turowski P., Majewska A., Polanska J., Ugorski M., Morty R.E., Motyl T.
Transcriptomic 'portraits' of canine mammary cancer cell lines with various phenotypes.
J. Appl. Genet. 51:169-183(2010)

PubMed=22235976; DOI=10.1111/j.1476-5829.2011.00269.x
Pawlowski K.M., Popielarz D.T., Szyszko K., Gajewska M., Motyl T., Krol M.
Growth hormone receptor (GHR) RNAi decreases proliferation and enhances apoptosis in CMT-U27 canine mammary carcinoma cell line.
Vet. Comp. Oncol. 10:2-15(2012)

Cross-references
Cell line collections (Providers) ATCC; CRL-3456
Encyclopedic resources Wikidata; Q54813828
Gene expression databases GEO; GSM724825
GEO; GSM724826
GEO; GSM724833
GEO; GSM724834
GEO; GSM1075089
GEO; GSM1075093
GEO; GSM1075097
GEO; GSM1290250
GEO; GSM1290251
GEO; GSM1889009
GEO; GSM1889010
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number19