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Cellosaurus CMT-U27 (CVCL_L335)

[Text version]
Cell line name CMT-U27
Synonyms Cell line 27; #27; CMT5
Accession CVCL_L335
Resource Identification Initiative To cite this cell line use: CMT-U27 (RRID:CVCL_L335)
Comments Doubling time: ~48 hours (PubMed=1375928); 54.7 hours (PubMed=20453304).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Canine mammary carcinoma (NCIt: C124249)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Poodle; VBO=VBO_0201048.
Sex of cell Female
Age at sampling 14Y
Category Cancer cell line
Publications

PubMed=1375928; DOI=10.1007/BF02877054
Eva Hellmen;
Characterization of four in vitro established canine mammary carcinoma and one atypical benign mixed tumor cell lines.
In Vitro Cell. Dev. Biol. Anim. 28:309-319(1992)

PubMed=9042250
Irma S. van Leeuwen, Eva Hellmen, Cees J. Cornelisse, Bart van der Burg, Gerard R. Rutteman;
p53 mutations in mammary tumor cell lines and corresponding tumor tissues in the dog.
Anticancer Res. 16:3737-3744(1996)

PubMed=19609018
Magdalena Krol, Karol M. Pawlowski, Janusz Stefan Skierski, Nagesha A.S. Rao, Eva Hellmen, Jan A. Mol, Tomasz Motyl;
Transcriptomic profile of two canine mammary cancer cell lines with different proliferative and anti-apoptotic potential.
J. Physiol. Pharmacol. 60 Suppl. 1:95-106(2009)

PubMed=20453304; DOI=10.1007/BF03195725
Magdalena Krol, Karol M. Pawlowski, Janusz Stefan Skierski, Pawel Turowski, Alicja Majewska, Joanna Polanska, Maciej Ugorski, Rory E. Morty, Tomasz Motyl;
Transcriptomic 'portraits' of canine mammary cancer cell lines with various phenotypes.
J. Appl. Genet. 51:169-183(2010)

PubMed=22235976; DOI=10.1111/j.1476-5829.2011.00269.x
Karol M. Pawlowski, Donald T. Popielarz, Katarzyna Szyszko, Malgorzata Gajewska, Tomasz Motyl, Magdalena Krol;
Growth hormone receptor (GHR) RNAi decreases proliferation and enhances apoptosis in CMT-U27 canine mammary carcinoma cell line.
Vet. Comp. Oncol. 10:2-15(2012)

Cross-references
Cell line collections (Providers) ATCC; CRL-3456
Encyclopedic resources Wikidata; Q54813828
Gene expression databases GEO; GSM724825
GEO; GSM724826
GEO; GSM724833
GEO; GSM724834
GEO; GSM1075089
GEO; GSM1075093
GEO; GSM1075097
GEO; GSM1290250
GEO; GSM1290251
GEO; GSM1889009
GEO; GSM1889010
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number19