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Cellosaurus Ace-1 (CVCL_L310)

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Cell line name Ace-1
Synonyms ACE-1
Accession CVCL_L310
Resource Identification Initiative To cite this cell line use: Ace-1 (RRID:CVCL_L310)
Comments Characteristics: Orthotopic injection of Ace-1 in dogs results in prostatic tumors with metastases to lungs and lymph nodes (PubMed=23335024).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Disease Canine prostate carcinoma (NCIt: C128122)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Labrador Retriever; VBO=VBO_0200800.
Hierarchy Children:
CVCL_E8GS (Ace-1-Luc)CVCL_DA11 (Ace-1(CMV))CVCL_DA12 (Ace-1(huGRPr))
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
Publications

PubMed=16683269; DOI=10.1002/pros.20408
Bruce E. LeRoy, Nanda K. Thudi, Murali Vara Prasad Nadella, Ramiro E. Toribio, Sarah H. Tannehill-Gregg, Adrie van Bokhoven, Deborah Davis, Stephanie Corn, Thomas John Rosol;
New bone formation and osteolysis by a metastatic, highly invasive canine prostate carcinoma xenograft.
Prostate 66:1213-1222(2006)

PubMed=21801068; DOI=10.2460/ajvr.72.8.1097
Tracy Stokol, Janelle L. Daddona, Lamya S. Mubayed, Jakob Trimpert, Sungkwon Kang;
Evaluation of tissue factor expression in canine tumor cells.
Am. J. Vet. Res. 72:1097-1106(2011)

PubMed=23335024; DOI=10.1002/pros.22642
Jill M. Keller, George R. Schade, Kimberly Ives, Xu Cheng, Thomas John Rosol, Morand Piert, Javed Siddiqui, William W. Roberts, Evan T. Keller;
A novel canine model for prostate cancer.
Prostate 73:952-959(2013)

PubMed=26940014; DOI=10.1002/pros.23172; PMCID=PMC5867903
Hai-Ming Ding, Shankaran Kothandaraman, Li Gong, Michelle M. Williams, Wessel P. Dirksen, Thomas John Rosol, Michael F. Tweedle;
A human GRPr-transfected Ace-1 canine prostate cancer model in mice.
Prostate 76:783-795(2016)

Cross-references
Cell line collections (Providers) ABM; T8280
Encyclopedic resources Wikidata; Q54608341
Entry history
Entry creation06-May-2013
Last entry update14-Aug-2025
Version number15