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Cellosaurus Ace-1 (CVCL_L310)

[Text version]
Cell line name Ace-1
Synonyms ACE-1
Accession CVCL_L310
Resource Identification Initiative To cite this cell line use: Ace-1 (RRID:CVCL_L310)
Comments Characteristics: Orthotopic injection of Ace-1 in dogs results in prostatic tumors with metastases to lungs and lymph nodes (PubMed=23335024).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Disease Canine prostate carcinoma (NCIt: C128122)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Labrador Retriever; VBO=VBO_0200800.
Hierarchy Children:
CVCL_DA11 (Ace-1(CMV))CVCL_DA12 (Ace-1(huGRPr))
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
Publications

PubMed=16683269; DOI=10.1002/pros.20408
LeRoy B.E., Thudi N.K., Nadella M.V.P., Toribio R.E., Tannehill-Gregg S.H., van Bokhoven A., Davis D., Corn S., Rosol T.J.
New bone formation and osteolysis by a metastatic, highly invasive canine prostate carcinoma xenograft.
Prostate 66:1213-1222(2006)

PubMed=21801068; DOI=10.2460/ajvr.72.8.1097
Stokol T., Daddona J.L., Mubayed L.S., Trimpert J., Kang S.
Evaluation of tissue factor expression in canine tumor cells.
Am. J. Vet. Res. 72:1097-1106(2011)

PubMed=23335024; DOI=10.1002/pros.22642
Keller J.M., Schade G.R., Ives K., Cheng X., Rosol T.J., Piert M., Siddiqui J., Roberts W.W., Keller E.T.
A novel canine model for prostate cancer.
Prostate 73:952-959(2013)

PubMed=26940014; DOI=10.1002/pros.23172; PMCID=PMC5867903
Ding H.-M., Kothandaraman S., Gong L., Williams M.M., Dirksen W.P., Rosol T.J., Tweedle M.F.
A human GRPr-transfected Ace-1 canine prostate cancer model in mice.
Prostate 76:783-795(2016)

Cross-references
Cell line collections (Providers) ABM; T8280
Encyclopedic resources Wikidata; Q54608341
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number14