Cellosaurus logo
expasy logo

Cellosaurus Man-12 (CVCL_L200)

[Text][XML][JSON]
Cell line name Man-12
Synonyms MAN-12; Man 12; MAN12; Man12; CMFTe002-A
Accession CVCL_L200
Resource Identification Initiative To cite this cell line use: Man-12 (RRID:CVCL_L200)
Comments Group: Clinical grade pluripotent cell line.
From: University of Manchester; Manchester; United Kingdom.
Registration: UK Stem Cell Bank (UKSCB); C-16-004, Steering comm. appl. SCSC12-27.
Omics: Genomics; Whole exome sequencing.
Omics: Variations; Array-based CGH.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Donor information: Embryo is sibling to that giving rise to Man-11 (Cellosaurus=CVCL_L199).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=26607962; DOI=10.1038/srep17258; PMCID=PMC4660465
Maurice A. Canham, Amy Lynnette Van Deusen, Daniel Roy Brison, Paul Alexandre De Sousa, Janet M. Downie, Liani Gasparini Devito, Zoe A. Hewitt, Dusko Ilic, Susan J. Kimber, Harry D. Moore, Helen Murray, Tilo Kunath;
The molecular karyotype of 25 clinical-grade human embryonic stem cell lines.
Sci. Rep. 5:17258.1-17258.13(2015)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

PubMed=28583200; DOI=10.1186/s13287-017-0561-y; PMCID=PMC5460457
Jin-Pei Ye, Nicola Bates, Despina Soteriou, Lisa Grady, Clare Edmond, Alex Ross, Alan Kerby, Philip A. Lewis, Tope Adeniyi, Ronnie Wright, Kay V. Poulton ...Show all 14 authors... , Marcus Lowe, Susan J. Kimber, Daniel Roy Brison; Show fewer authors
High quality clinical grade human embryonic stem cell lines derived from fresh discarded embryos.
Stem Cell Res. Ther. 8:128.1-128.13(2017)

Cross-references
Cell line databases/resources hPSCreg; CMFTe002-A
Biological sample resources BioSamples; SAMEA4760722
Encyclopedic resources Wikidata; Q54903988
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number16