| Cell line name |
LNCaP-LN3 |
|---|
| Synonyms |
LNCaP-LN-3 |
|---|
| Accession |
CVCL_L162 |
|---|
| Resource Identification Initiative |
To cite this cell line use: LNCaP-LN3 (RRID:CVCL_L162) |
|---|
| Comments |
Population: Caucasian.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056. |
|---|
| Sequence variations |
- Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
- Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
|
|---|
| Disease |
Prostate carcinoma (NCIt: C4863) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_L161 (LNCaP-LN2)
Children:
|
|---|
| Sex of cell |
Male |
|---|
| Age at sampling |
50Y |
|---|
| Category |
Cancer cell line |
|---|
| Publications | PubMed=9816342
Curtis A. Pettaway, Sen Pathak, Graham Greene, Edilberto Ramirez, Michael R. Wilson, Jerald J. Killion, Isaiah Joshua Fidler;
Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice.
Clin. Cancer Res. 2:1627-1636(1996) PubMed=12725112; DOI=10.1385/1-59259-372-0:21
Pamela J. Russell, Elizabeth A. Kingsley;
Human prostate cancer cell lines.
Methods Mol. Med. 81:21-39(2003) |
|---|
| Cross-references |
|---|
| Cell line collections (Providers) |
KCLB; 80018
|
|---|
| Cell line databases/resources |
cancercelllines; CVCL_L162
|
|---|
| Encyclopedic resources |
Wikidata; Q54902840
|
|---|
| Entry history |
|---|
| Entry creation | 06-May-2013 |
|---|
| Last entry update | 19-Dec-2024 |
|---|
| Version number | 17 |
|---|
