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Cellosaurus UM-SCC-63 (CVCL_L130)

[Text version]
Cell line name UM-SCC-63
Synonyms UMSCC-63; UMSCC 63; UMSCC63; University of Michigan-Squamous Cell Carcinoma-63
Accession CVCL_L130
Resource Identification Initiative To cite this cell line use: UM-SCC-63 (RRID:CVCL_L130)
Comments Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Transformant: NCBI_TaxID; 10585; Human papillomavirus type 31 (HPV31).
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys242Phe (c.725G>T); ClinVar=VCV000376578; Zygosity=Unspecified (PubMed=1394225).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=1851275; DOI=10.1177/019459989110400304
Bradford C.R., Zacks S.E., Androphy E.J., Gregoire L., Lancaster W.D., Carey T.E.
Human papillomavirus DNA sequences in cell lines derived from head and neck squamous cell carcinomas.
Otolaryngol. Head Neck Surg. 104:303-310(1991)

PubMed=1394225
Somers K.D., Merrick M.A., Lopez M.E., Incognito L.S., Schechter G.L., Casey G.
Frequent p53 mutations in head and neck cancer.
Cancer Res. 52:5997-6000(1992)

PubMed=8552396
Patel A.M., Incognito L.S., Schechter G.L., Wasilenko W.J., Somers K.D.
Amplification and expression of EMS-1 (cortactin) in head and neck squamous cell carcinoma cell lines.
Oncogene 12:31-35(1996)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_L130
Encyclopedic resources Wikidata; Q54990896
Entry history
Entry creation06-May-2013
Last entry update05-Oct-2023
Version number9