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Cellosaurus WM3268 (CVCL_L031)

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Cell line name WM3268
Synonyms WM-3268; WM 3268; WM3268V; WM-3268V; WM 3268V; WM3268A
Accession CVCL_L031
Resource Identification Initiative To cite this cell line use: WM3268 (RRID:CVCL_L031)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (Wistar).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (Wistar).
  • Mutation; HGNC; HGNC:1097; BRAF; None_reported; -; Zygosity=- (Wistar).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (Wistar).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO11,12
D2S133817,18
D3S135813,16
D5S8189,10
D7S8209,12
D8S117913,14
D13S3178,13
D16S53911
D18S5115,18
D19S43312,13
D21S1129,32.2
FGA22,23
TH016,9.3
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Keiran S.M. Smalley, Rooha Contractor, Thiennga K. Nguyen, Min Xiao, Robin Edwards, Viswanathan Muthusamy, Alastair J. King, Keith Thomas Flaherty, Marcus W. Bosenberg, Meenhard Herlyn, Katherine L. Nathanson;
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Rockland; WM3268-01-0001
Cell line databases/resources cancercelllines; CVCL_L031
Encyclopedic resources Wikidata; Q54994246
Gene expression databases GEO; GSM109038
GEO; GSM185198
GEO; GSM185199
Polymorphism and mutation databases Cosmic; 1155561
Cosmic; 1303072
Progenetix; CVCL_L031
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number20