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Cellosaurus (CVCL_KY11)

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Comments Characteristics: Using homologous recombination the Sox1 reading frame was replaced by a GFP-IRES-PuroR construct. Expresses eGFP under the control of the Sox-1 promoter (from parent cell line).
Doubling time: ~24 hours (PubMed=16086633).
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Genetic integration: Method=Homologous recombination; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Homologous recombination; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Neural stem cell; CL=CL_0000047.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10090)
Breed/subspecies: 129P2/Ola.
Hierarchy Parent: CVCL_Y482 (46C)
Sex of cell Male
Age at sampling Blastocyst stage
Category Somatic stem cell
Entry history
Entry creation20-May-2021
Last entry update14-Aug-2025
Version number10