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Cellosaurus (CVCL_KW57)

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Comments Problematic cell line: Contaminated. Shown to be a M14 derivative (PubMed=18713817; PubMed=20143388; PubMed=21868764). Originally thought to originate from a thyroid gland papillary carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00246.
Population: Caucasian.
Derived from site: Metastatic; Right buttock, hypodermis; UBERON=UBERON_0013691+UBERON_0002072.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; c.150+2T>C (IVS1+2T>C); ClinVar=VCV000406712; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; c.455insCdel26; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Heterozygous (PubMed=8423216; PubMed=14522906).
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1395 (M14)
Sex of cell Male
Age at sampling 33Y
Category Cancer cell line
STR profile Source(s): PubMed=18713817; PubMed=21868764

Markers:
AmelogeninX
CSF1PO11
D13S31712
D16S5399,13
D18S5113,17
D21S1130
D3S135814,16
D5S81811,12
D7S8208
D8S117913
FGA21
TH016,7
TPOX8,11
vWA16,18

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Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number33