Cellosaurus logo
expasy logo

Cellosaurus (CVCL_KV51)

[Text][XML][JSON]
Comments Microsatellite instability: Stable (MSS) (PubMed=12661003; Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; miRNA profiling; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:1748; CDH1; Simple; c.1712-1G>A; Zygosity=Homozygous; Note=Splice acceptor mutation (PubMed=19593635).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Asp92His (c.274G>C); Zygosity=Heterozygous (PubMed=19593635; ATCC=HTB-21).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Thr (c.839G>C); ClinVar=VCV000012368; Zygosity=Homozygous (PubMed=16541312; ATCC=HTB-21; Cosmic-CLP=946382; DepMap=ACH-000783).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*02:01,32:01
HLA-BB*15:01,40:02
HLA-CC*02:02,03:03
Class II
HLA-DQDQA1*05:02,03:02
DQB1*03:04,03:04
HLA-DRDRB1*11:30,13:07
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.37
Native American0
East Asian, North1.38
East Asian, South0
South Asian0
European, North66.52
European, South31.74
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): ATCC=HTB-21; Cosmic-CLP=946382; PubMed=25877200; Technion Genomics Center

Markers:
AmelogeninX
CSF1PO10,12
D10S124814,17
D12S39115
D13S31712
D16S53911
D18S5114,15
D19S43313
D1S165611,15
D21S1132.2
D22S104511,17
D2S133817,21
D2S44111
D3S135818
D5S81812,13
D7S8208,11
D8S117912,13
FGA19,25
Penta D10,11
Penta E12,14
TH018,9.3
TPOX8
vWA15

Run an STR similarity search on this cell line
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number49